liver on the first-pass through hydrolysis (Micromedex, 2019). The majoring of the drug (83%) is excretedin fecal matter and 10% excreted by the kidneys (Micromedex, 2019). It is essential to monitor lipid panels prior to drug initiation and periodically throughout treatment to evaluate effectiveness and dosing requirements. In addition to lipid panels liver function tests and creatine kinase levels must be monitored to ensure proper liver and kidney function (Micromedex, 2019).
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ReferencesEdmunds, M. W., & Mayhew, M. S. (2014).Pharmacology for the primary care provider, 4th ed. St. Louis, MO: Elsevier Mosby.Epocrates. (2019). Retrieved from Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G., Zimmerman, R. S., Bailey, T. S., … Zangeneh, F. (2015). American Association of Clinical Endocrinologists and American College of Endocrinology--Clinical Practice Guidelines for Developing a Diabetes Mellitus Comprehensive Care Plan--2015--Executive Summary. Endocrine Practice: Official Journal Of The American College Of Endocrinology And The American Association Of Clinical Endocrinologists, 21(4), 413–437. Retrieved from shib&db=mdc&AN=27408942&site=eds-live&scope=siteMicromedex. (2019). Retrieved from
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