Electrocardiograph
ECG – waves and segments
P- wave
QRS – wave
T- wave
PR - interval
QRS - interval
QT- interval
PQ – segment
ST – segment
SA node must depolarize
Ventricular
Depolarization
QT intervial tells us about the action potential of the myocyte

Summary

Disorders
Most problems caused by disjunction of electrical
system
Arrhythmia
– abnormal cardiac rhythm
1.
Heart Block (varies in degrees) – failure in
conduction system
2.
Atrial flutter – extra beats of the atrial
muscle
3.
Premature ventricular contractions (PVC’s) –
extra beat
4.
Ventricular fibrillation – electrical signals
arrive at
ventricular myocytes at different
times
5.
Myocardial infarction
6.
Long QT
7.
Electrolyte disturbances

•
Heart Block – electrical
signal disrupted between
atria
and ventricles
i.
First degree
ii.
Second degree
iii.
Third degree
(complete)
Disorders

Electrocardiograph
•
Nodal Rhythm –
no SA node input
, AV node
pacemaker –
50 bpm
Which wave is
missing?

•
Atrial Flutter: rapid heart beat (tachycardia)
250-300 bpm
2:1 QRS usually present (QRS max out at
250 bpm)
•
Atrial Fibrillation: rapid heart beat (tachycardia)
300-500 bpm
Disorders

•
PVC’s (extrasystole) – usually originate in left
ventricle
i.
Inverted, misshapen QRS wave
Disorders

•
Ventricular fibrillation– erratic firing of
ventricular
myocytes,
unsynchronized
contraction
Disorders

•
Myocardial Infarction (MI)
i.
ST elevation
ii.
T- wave inversion
Disorders

•
Long QT syndrome
i.
Ion channel mutations (K
+
, Ca
2+
, Na
+
)
ii.
Leads to ventricular tachycardia, and death
Disorders
Longer to repolarize
Na or Ca stays on
K doesn’t turn on

•
Changes in Plasma K
+
: most relevant
electrolyte disturbance
Disorders
Hyperkalemia leads to death

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- Spring '17
- Cardiac electrophysiology, Sinoatrial node, ventricular tachycardia, Ventricular fibrillation, Cardiac Myocyte