Mechanical properties of actin tubulin and intermediate filament microtubule

Mechanical properties of actin tubulin and

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What make the intermediate filaments? Structure of Intermediate Filament Polypeptides?
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Centrosome o serves as the microtubule organizing center Proteins that can stabilize the growing microtubule or cause it to rapidly disassociate o MAP (microtubule associated protein) o Catastrophin Microtubule motor proteins: they move vesicles and organelles o Kinesins (go towards plus end) o Dyneins (go towards minus end, “dying”) Microtubules and mitosis: o Microtubules help to align chromosome during mitosis o Microtubules along with motor proteins separate daughter chromosomes as well as push the two centrosomes apart Kinesin helps to push the microtubules away from each other Dynein pulls the centrosome to one side of the membrane Actin Assembly doesn’t come from just one point it can come any where in the cell , what actually happens is actin there are proteins that tells where the branch will start they allways have a sertn , you can control where actin polymerize Structure o Actin fibers like microtubules are unstable o Made stable by interactions with other proteins “actin binding proteins” o Differential interactions determine “stiffness” of the structure o Highly organized Formins and actin-related proteins (ARPs) control actin assembly Actin motor protein : Myosin ( contracting the cell ) o Slide actin filaments over each other = shortening of actin bundle o The myosin head “walks” towards the actin plus end of the actin causing contraction Cell movement: o
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  • Spring '14
  • GaryL.Bowlin

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