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E55-2010 problem set 01 KEY

Reliable prediction of the events that will transpire

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reliable prediction of the events that will transpire during development—it never tells us the commitment of a cell at any particular stage. Commitment is only ascertained by discrete experimental tests. To test specification, the eye progenitor would need to be isolated and allowed to develop in a neutral environment; to test determination, the eye progenitor would need to be isolated and placed into another distinct environment in the embryo and tested for whether or not it still formed an eye. 5. What does this experiment suggest about the mechanism of development that is operative with regard to the eye? In your answer, clearly define the difference between mosaic and regulative mechanisms of development. In this experiment, you removed the eye progenitor and yet an eye developed later on in embryogenesis. This finding tells you that other embryo cells are competent to become an eye in the absence of the eye progenitor, thus a regulative mechanism of development is suggested. In
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