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A/E: nausea, heartburn, GI issues, headache, drowsiness, constipationAssess glucose levels, pain, ROM, & GIDr. Cavanaugh said in class patient may need to be on med for at least 60 days before notice effectivenessContact HCP if gastric discomfort develops and persistsTake prior to mealsMust be taken consistently to workAntihistamine (Benadryl, Claritin, Zyrtec, Allegra) ●To prevent release of histamines (mast cells), block at H1 receptor●Dries secretions, dry mouth, can cause drowsiness, be careful of additive effects, urinary retention●Treats colds and allergic rhinitis●Anticholinergic effects●Do not take with other CNS depressants (ie: alcohol)●Can have opposite effects in young children/ Geri pts (diphenhydramine = benadryl) a.k.a paradoxical effects●Don’t exceed more than 300 mg/day●AE: hypotension, anorexia, dry mouth, palpitations, dysuria, depression, blurred vision●First generations make you drowsy●Contraindications in acute asthma attacksTopical antifungal (-azole)●Assess for signs of contact dermatitis occasionally patients react to the topical medications used●Make sure patients are treating right infection—topical are OTC; self-diagnose●Meds may be “swished and swallowed” or “swish and spit” to treat candidiasis●Monitor for N/V/D with high doses●May have effects on bone marrow function, watch for bone marrow depression●Diflucan (Fluconazole)○LIVER- hepatotoxicity●Ciclopirox topical lacquer for nails●Topical Creams - skin lecture○OTC: clotrimazole, miconazole○Rx: Ketoconazole (yeast), Econazole (tinea), Ciclopirox (both)Antitussive-Dampen the cough reflex, relieves non-productive cough-Used for common cold or allergies-Liquid syrups should be allowed to coat throat- no water-Opioid- raise cough threshold in CNS (Codeine, Hydrocodone)-Non-Opioid--Dextromethorphan- raises cough threshold in CNS-Large amounts: Hallucination, slurred speech, dizzy, drowsy, euphoria, resp. depression, ataxia, seizure, coma
-Benzonatate- numbs stretch receptors in lungsDo not want to use these w/COPD, chronic bronchitis, asthma, smoking, cystic fibrosis (you want cough) Oxybutynin (Ditropan XL)- this is the gel form· Pharm class: AnticholinergicTherapeutic class: urinary tract antispasmodicIndications: Urinary symptoms that may be associated with neurogenic bladderincluding:Frequent urination, Urgency, Nocturia, Urge incontinence.Overactive bladderwith symptoms of urge incontinence, urgency, and frequency.Action: Inhibits the action of acetylcholine at postganglionic receptors.Has direct spasmolytic action on smooth muscle, including smooth muscle lining the GU tract, without affecting vascular smooth muscle.Therapeutic Effect(s):Increased bladder capacity.Delayed desire to void.