BSF3232-METHOD VALIDATION&VERIFICATION 11415

An uncertainty is given in the form of a standard

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An uncertainty is given in the form of a standard deviation,  s, u(x) a relative standard deviation,  s, u(x) = x(s/x)  or a coefficient of variance, CV% without specifying the CV%  distribution u(4= 100  An uncertainty is given in the form of a  95%  (or other) u(x) = c12 (for  at  confidence interval x  ±   without specifying the distribution 95%)  u(x) = c13 (for  at  99.7%)  Rectangular distribution When Uncertainty  A certificate or other specification gives limits without / ux)----1=  specifying a level of confidence (e.g. 25m1  ±  0.05m1) Where a = semi-  An estimate is made in the form of a maximum range ( ±  a)  with no knowledge of the shape of the distribution range or half-width  between the upper  and lower limits 16 
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CONFIDENTIAL BSK/BSB/BSP/1 41 511BSF3232  Triangular distribution  When Uncertainty  The available information concerning x is less limited for a , ut'x)=—i=  rectangular distribution. Values close to x are more likely than near the bounds.  An estimate is made in the form of a maximum range ( ±  a)  described by a symmetric distribution Statistical formula  S =   SD001 [(n i  —1)xs +( 2  —1)xs +...  (n1—l)+(n2-1)+... RSDOOI F L n L : ^_ I)xRSD  +(n2  —1)xRSD +...  (n1 —l)+(n2 —1)+...  Estimation of precision from duplicate analysis  S =-L11 -,2I2 R I T2p ,  When multiple references are used  u(bias)  t jRM ias  Uiej  p1/1s2 (bias2)1  bias When single reference material is used  = (^ n +Ue  u(bias) Uncertainty from recovery study (CRM available)  u2(— ((- C 1UC )') U(Rm)RmX1(02)+ crm obs crm 17 
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CONFIDENTIAL BSK/BSB/BSP/141 51/BSF3232  Uncertainty from recovery study (No CRM, only spiking)  fr   U(Rrn)Rrn nx(obS)2  J +   C.p,ke  Significant testing on Recovery  t=  11 —  —R,,l 18
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