effect on norepinephrine and little affinity for cholinergic (hypotension dry oral secreations), histaminic, or alpha- adrenergic sites • Indications – Depression, OCDs, panic attacks, bulimia, PMDD, posttraumatic stress disorders, social phobias, social anxiety disorders
Copyright © 2017 Wolters Kluwer • All Rights Reserved Selective Serotonin Reuptake Inhibitors (cont.) Selective Serotonin Reuptake Inhibitors (cont.) • Pharmacokinetics – Absorbed from the GI tract – Metabolized in the liver – Associated with congenital abnormalities • Contraindications – Known allergy, pregnancy, lactation, impaired renal function or hepatic function
Copyright © 2017 Wolters Kluwer • All Rights Reserved Selective Serotonin Reuptake Inhibitors (cont.) Selective Serotonin Reuptake Inhibitors (cont.) • Adverse Reactions – Headache, drowsiness, dizziness, insomnia, anxiety, tremor, agitation • Drug-to-Drug Interactions – MAOIs – TCAs increase of therapeutic and toxic effect
Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for SSRI Antidepressant Agents Nursing Considerations for SSRI Antidepressant Agents • Assessment: History and Physical Exam • Nursing Diagnosis • Implementation • Evaluation • Medication doesn’t work thus other docs giving more SSRI therefore can get seratonin strom
Copyright © 2017 Wolters Kluwer • All Rights Reserved Miscellaneous Antidepressants Miscellaneous Antidepressants • Bupropion ( Wellbutrin, Zyban ): anticholigic effects if taken for a long time • Mirtazapine ( Remeron ): common SE patient is going to like to eat, lower dose given to people that need an appetite stimulants • Nefazodone ( Serzone ) • Trazodone ( Desyrel ): all the time to treat insomnia • Venlafaxine ( Effexor )
Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 22: Psychotherapeutic Agents Chapter 22: Psychotherapeutic Agents
Copyright © 2017 Wolters Kluwer • All Rights Reserved Psychotherapeutic Agents Psychotherapeutic Agents • Used to treat psychoses – perceptual and behavioral disorders • Drugs do not cure the disorder – help patients (symptoms to live in the society safely) function in a more acceptable manner and carry on activities of daily living • Used in both children and adults
Copyright © 2017 Wolters Kluwer • All Rights Reserved Mental Disorders and Their Classification Mental Disorders and Their Classification • Schizophrenia • Mania/Bipolar Disease • Narcolepsy • Attention-Deficit Disorder
Copyright © 2017 Wolters Kluwer • All Rights Reserved Schizophrenia Schizophrenia • Characteristics – Hallucinations, paranoia, delusions, speech abnormalities, and affective problems • Causes – Strong genetic association – May reflect a fundamental biochemical abnormality
Copyright © 2017 Wolters Kluwer • All Rights Reserved Mania/Bipolar Illness Mania/Bipolar Illness • Characteristics – Mania: Periods of extreme overactivity and excitement – Bipolar illness: (2)Extremes of depression followed by hyperactivity and excitement (manic) these symptoms do not have these two feelings in the same time frame • Cause – May reflect a biochemical imbalance followed by overcompensation on the part of neurons and their inability to re-establish stability
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- Fall '19
- Mark Daco
- Selective serotonin reuptake inhibitor, Antidepressant, Wolters Kluwer Health