effect on norepinephrine and little affinity for cholinergic
(hypotension dry oral secreations), histaminic, or alpha-
adrenergic sites
•
Indications
–
Depression, OCDs, panic attacks, bulimia, PMDD,
posttraumatic stress disorders, social phobias, social
anxiety disorders
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Selective Serotonin Reuptake Inhibitors
(cont.)
Selective Serotonin Reuptake Inhibitors
(cont.)
•
Pharmacokinetics
–
Absorbed from the GI tract
–
Metabolized in the liver
–
Associated with congenital abnormalities
•
Contraindications
–
Known allergy, pregnancy, lactation, impaired renal
function or hepatic function
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Selective Serotonin Reuptake Inhibitors
(cont.)
Selective Serotonin Reuptake Inhibitors
(cont.)
•
Adverse Reactions
–
Headache, drowsiness, dizziness, insomnia, anxiety,
tremor, agitation
•
Drug-to-Drug Interactions
–
MAOIs
–
TCAs increase of therapeutic and toxic effect
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Nursing Considerations for SSRI
Antidepressant Agents
Nursing Considerations for SSRI
Antidepressant Agents
•
Assessment: History and Physical Exam
•
Nursing Diagnosis
•
Implementation
•
Evaluation
•
Medication doesn’t work thus other docs giving more
SSRI therefore can get seratonin strom
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Miscellaneous Antidepressants
Miscellaneous Antidepressants
•
Bupropion (
Wellbutrin, Zyban
): anticholigic effects if
taken for a long time
•
Mirtazapine (
Remeron
): common SE patient is going to
like to eat, lower dose given to people that need an
appetite stimulants
•
Nefazodone (
Serzone
)
•
Trazodone (
Desyrel
): all the time to treat insomnia
•
Venlafaxine (
Effexor
)
Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins
Chapter 22:
Psychotherapeutic Agents
Chapter 22:
Psychotherapeutic Agents
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Psychotherapeutic Agents
Psychotherapeutic Agents
•
Used to treat psychoses – perceptual and behavioral
disorders
•
Drugs do not cure the disorder – help patients (symptoms
to live in the society safely)
function in a more acceptable
manner and carry on activities of daily living
•
Used in both children and adults
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Mental Disorders and Their Classification
Mental Disorders and Their Classification
•
Schizophrenia
•
Mania/Bipolar Disease
•
Narcolepsy
•
Attention-Deficit Disorder
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Schizophrenia
Schizophrenia
•
Characteristics
–
Hallucinations, paranoia, delusions, speech
abnormalities, and affective problems
•
Causes
–
Strong genetic association
–
May reflect a fundamental biochemical abnormality
Copyright © 2017 Wolters Kluwer • All Rights Reserved
Mania/Bipolar Illness
Mania/Bipolar Illness
•
Characteristics
–
Mania: Periods of extreme
overactivity and excitement
–
Bipolar illness: (2)Extremes of
depression followed by
hyperactivity and excitement (manic) these symptoms
do not have these two feelings in the same time frame
•
Cause
–
May reflect a biochemical imbalance followed by
overcompensation on the part of neurons and their
inability to re-establish stability
You've reached the end of your free preview.
Want to read all 67 pages?
- Fall '19
- Mark Daco
- Selective serotonin reuptake inhibitor, Antidepressant, Wolters Kluwer Health
