Flovent 220 mcginh 2 inh BID Flovent 250 mcginh 1 2

Flovent 220 mcginh 2 inh bid flovent 250 mcginh 1 2

This preview shows page 2 - 4 out of 4 pages.

(Flovent HFA) 44, 110, 220 mcg/inh 2 inh BID Flovent Diskus: 50, 100, 250 mcg/inh 1-2 inh BID Arnuity Ellipta: 100, 200 mcg/inh 1-2 inh QD ArmonAir RespiClick: 55, 113, 232 mch/inh 1-2 inh BID Mometasone: Asmanex HFA: 100, 200 mcg/inh 1-2 inh BID Asmanex Twisthaler: 110, 220 mcg/inh 1-2 inh QD MDIs: Contain HFA, Respimat, or no suffix Deliver dose of aerosolized liquid medication Some use a propellant (HFA) Admin requires a slow deep inhalation at the same time as pressing the canister to deliver the dose Spacer can be used Shake well except for: QVAR, ALvesco, and Respimat products DPIs: Diskus, Ellipta, Pressair, Handihaler, Neohaler, RespiClick Deliver a dose of powdered medication No propellant Admin requires a quick and forceful inhalation (no coordination needed) Spacers cannot be used Do not shake LRTAs: Zafirlukast and zileuton CI in hepatic impairment SE: HA Drug Dosing Montelukast: inhibits LTD4 -minor 3A4 and 2C8/9 substrate (gemfibrozil inc and lumacaftor dec) 10 mg in the evening 6-14 YO: 5 mg PO HS 1-5 YO: 4 mg PO HS Granules may be admin directly in mouth, dissolved in 5 mL of breastmilk/formula or mixed with spoonful of applesauce. Do NOT mix in anything else and use within 15 min of opening packet Zafirlukast: inhibits LTD4 and LTE4 -major 2C9 substrate; weak 2C8 and moderate 2C9 inhibitor -Inc levels of carvedilol, theophylline, and warfarin -Dec levels by erythromycin and warfarin 20 mg PO BID 5-11 YO: 10 mg BID 1 hour before/2 hrs after meals Keep in original container Zileuton: inhibits 5- lipoxygenase which inhibits leukotriene formation Zyflo: 600 mg QID Zyflo CR: 1200 mg BID within 1 house after morning and evening meals
Image of page 2
-Minor 1A2, 2C9, and 3A4 substrate and weak 1A2 inhibitor -Inc levels of pimozide, propranolol, theophylline, and warfarin Not recommended in <12 YO Theophylline: blocks phosphodiesterase inc cAMP and releases EPI from the adrenal medulla cells resulting in bronchodilation but also causing diuresis, CNS/cardiac stimulation, and gastric acid secretion Active metab: caffeine and 3- methylxanthine LD: 5 mg/kg IBW (or TBW if<IBW) MD: 300-600 mg QD Tx range: 5-15 mcg/mL (measure peak at SS after 3 days of PO dosing) SE: N/V To convert from aminophylline, multiply by 0.8 Major 1A2 and minor 3A4 and 2E1 substrate Saturable kinetics (first order then zero order) Drugs that inc levels (1A2 inhibition): cimetidine, cipro, fluvoxamine, propranolol, zafirlukast, zileuton Drugs that inc levels (3A4 inhibition): clarith, eryth
Image of page 3
Image of page 4

You've reached the end of your free preview.

Want to read all 4 pages?

  • Summer '17

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture

  • Left Quote Icon

    Student Picture