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Ulcerative colitis 8 which of the following

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Ulcerative colitis8.Which of the following statements aretrue in ulcerative colitis (UC)?AIn 95 per cent of cases, the diseasestarts in the rectum and spreadsproximally.BIt is a diffuse disease affecting all thelayers of the large bowel.CGranulomas are a typical microscopicfeature.DThe transverse colon is affected in toxicmegacolon.EPatients may present as an emergencywith fulminating colitis in 5–10 per cent.9.Which of the following is not acomplication of UC?ACarcinomaBPrimary sclerosing cholangitisCInternal fistulaeDAnkylosing spondylitisEPerforation.10. Which of the following is not abarium enema finding in UC?ALoss of haustrationsBNarrow contracted colonCIncrease in the presacral spaceDCobblestone appearanceEBackwash ileitis.11. What is colonoscopy routinely usedfor in UC?ATo assess the extent of the diseaseBTo distinguish it from Crohn’s diseaseCTo monitor the response to treatmentDTo carry out surveillance for thedevelopment of cancerETo assess severity in acute cases.12. Which of the following criteria do notindicate severe disease in UC?AMore than four motions a dayBPyrexia of over 37.5°CCTachycardia >90/minDTachypnoea >20/minEHypoalbuminaemia <30 g/L.13. Which UC patients have an enhancedrisk of developing cancer?AThose who have had the disease sincechildhood.BThose who have had the disease forover 10 years.CThose who have had a very severe firstattack.DThose who have the entire colon involved.EThose who have another member ofthe family with the disease.14. Which of the following drugs are notused in the medical treatment of UC?APrednisoloneB5-ASA compoundsCPredsol enemaDAzathioprineEIsoniazid.15. In the management of a severe attackof UC, which of the following is nottrue?AEvery patient needs a proctocolectomyafter resuscitation.BDaily plain abdominal X-ray is taken toassess transverse colon dilatation.CParenteral high-calorie alimentation isinstituted.DIntravenous hydrocortisone is given.EAzathioprine or cyclosporin A is given.16. What are the indications for surgeryin UC?ASevere fulminating disease notresponding to vigorous medicaltreatment.BSevere dysplastic change or cancer onbiopsy.CNon-compliance of medical treatment.DChronic steroid-dependent diseaserequiring large doses.EExtraintestinal disease.17. Which of the following statementsregarding surgery in UC is false?AIn the emergency situation, totalabdominal colectomy and ileostomyshould be the procedure of choice.BProctocolectomy and ileostomy areassociated with the lowest complicationrate.
ABDOMINAL476CRestorative proctocolectomy with anileoanal pouch should be considered inall patients.DColectomy with ileorectal anastomosis isthe most favoured procedure.EIleostomy with a continent intra-abdominal pouch is not often done.

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