APh161_Lecture1

Replisome proteosome ribosome a single molecule

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Unformatted text preview: Replisome Proteosome Ribosome A Single Molecule Census of the Cell A Single Molecule Census of the Cell 20-40% of the protein stockpile consists of integral membrane proteins. An estimate: roughly 500 copies each of 1000 different membrane proteins. ½ of the cell surface area is dedicated to these proteins. 2 microns Not a full census: lipopolysaccharides, peptidoglycan, etc.. – that is fun too! A Single Molecule Census of the Cell: The A Single Molecule Census of the Cell: The Parts List Parts List Crick’s great polymer languages A Single Molecule Census of the Cell: The A Single Molecule Census of the Cell: The Parts List Parts List A Single Molecule Census of the Cell A Single Molecule Census of the Cell A Single Molecule Census of the Cell: A Single Molecule Census of the Cell: Part 2 Part 2 Collections of Cells - Sporulation Collections of Cells - Sporulation Collections of Cells - Tissues Collections of Cells - Tissues Collections of Cells - Organisms Collections of Cells - Organisms Featured above is a digital image of a triple- labeled Drosophila embryo at the cellular blastoderm stage. The specimen was immunofluorescently labeled with antibodies to the hairy protein in red, Kruppel in green, and giant in blue. This amazing image won the BioTechniques cover of the year award in 1993. From Stephen Paddock. C Elegans – a worm with 959 cells C Elegans – a worm with 959 cells...
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  • Fall '09
  • molecular biology, DNA, Single Molecule Census, Quantitative Models Demand Quantitative Experimentation, Single Molecule Biophysics

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