HK 3810 Package 2 Kidneys.docx

Decrease in left ventricle function decrease map

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decrease in left ventricle function decrease MAP Response to decrease in MAP: High pressure baroRc increase SNS, decrease PNS o Nodal cells of heart increase HR increase CO increase MAP o Ventricular myocytes of heart increase contractility increase SV increase CO increase MAP o Arterioles vasoconstrict increase TPR increase MAP o Veins venoconstriction increase MCFP increase VR increase CO or right heart… increase CO of left heart increase MAP
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HK 3810 Package 2 Kidneys o Adrenal glands increase epi/NE supports all of the above steps o Kidney increase renin increase AII Increase ADH vasoconstrict afferent > efferent decrease GFR Increase H2O reabsorption increase blood volume increase MAP Vasoconstrict increase TPR increase MAP Increase ALDO increase Na+ reabsorption increase H2O reabsorption increase blood volume increase MAP Low pressure baroRc increase ADH Atrial stretch Rc High pressure baroRc at kidney Fluid flux Time scales ms-sec neuron effects, fluid flux sec-min hormones hours at kidney (H2O loss/reabsorption)
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  • Fall '16
  • Coral Murrant
  • Kidney anatomy, Nephron, decrease

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