A Life Decoded My Genome My Life Penguin 2007 in which he relates the history

A life decoded my genome my life penguin 2007 in

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A Life Decoded: My Genome: My Life (Penguin, 2007) in which he relates the history of the Human Genome Project, discusses the implications of this kind of information, and relates it back to his own life. I highly encourage you to read this book when you have time. There are a series of vignettes in the book in which Craig Venter discusses specific genes that relate to a human disorder or trait. He then examines the specific allele variants that he is carrying (diploid genotype). You will be given one of these vignettes and asked to discuss the following: Gene name Short description of the condition or disorder Cytological location Gene structure (intron/exon structure; alternate splice variants) Gene product (protein, RNA) Gene expression patterns (tissues, developmental timing) Gene product function Consequences of mutant alleles Allele variants – sequence differences, loss of function/gain of function, etc. Distribution of alleles Implications for diagnosis, prediction, treatment, … The project should be done in groups of three (or two) - ALL members of the group must contribute to the collection and preparation of the project material. Your project will then be presented in two formats: 1) An oral presentation in your tutorial during the three weeks between October 25th and November 12th.
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