Adverse Effects Headache dizziness myalgia nausea diarrhea and abdominal pain

Adverse effects headache dizziness myalgia nausea

This preview shows page 33 - 43 out of 45 pages.

Leukotriene Receptor Antagonists (cont.) Adverse Effects Headache, dizziness, myalgia, nausea, diarrhea and abdominal pain, elevated liver enzyme concentrations, vomiting, and generalized pain Drug-to-Drug Interactions Propranolol, theophylline, terfenadine, or warfarin Calcium channel blockers, cyclosporine, or aspirin
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Leukotriene Receptor Antagonists Nursing Considerations for Leukotriene Receptor Antagonists Assess: History and Physical Exam and known allergy Acute bronchospasm or asthmatic attack Impaired renal or hepatic function Temperature, orientation and affect
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Leukotriene Receptor Antagonists Prototype Leukotriene Receptor Antagonists
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Lung Surfactants Lung Surfactants Naturally occurring compounds or lipoproteins containing lipids and apoproteins that reduce the surface tension within the alveoli, allowing expansion of the alveoli for gas exchange ( Survanta ), calfactant ( Infasurf ), the newest drug of the class Lucinactant ( Surfaxin ) Poractant ( Curosurf )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Lung Surfactants Lung Surfactants Actions Replace the surfactant that is missing in the lungs of neonates with RDS Indications Rescue treatment of infants who have developed RDS Pharmacokinetics Begin to act immediately on instillation into the trachea Metabolized in the lungs
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Lung Surfactants (cont.) Lung Surfactants (cont.) Contraindications -Emergency drug; no contraindication Adverse Effects Patent ductus arteriosus Hypotension Intraventricular hemorrhage Pneumothorax Pulmonary air leak Hyperbilrubinemia Sepsis
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Lung Surfactants Nursing Considerations for Lung Surfactants Assess: History and Physical Exam and known allergy Time of birth and exact weight Temperature, Respirations, adventitious sounds, endotracheal tube placement and patency, and chest movements Blood pressure, pulse, and arterial pressure Blood gases and oxygen saturation
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Lung Surfactants Prototype Lung Surfactants
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Mast Cell Stabilizers Mast Cell Stabilizers Actions- Works at the cellular level to inhibit the release of histamine and inhibits the release of SRSA Indications-Treatment of chronic bronchial asthma Exercise induced asthma Allergic rhinitis It is no longer considered part of the treatment standards because of the availability of more specific and safe Cromolyn ( NasalCrom )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved
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