NBDE Microbiology/Pathology Flashcards

Terms Definitions
The organism most responsible for causing acute necrotizing ulcerative gingivitis is?
a) anaerobic bacteria
b) gram + bacteria
c) fungi
d) gram - bacteria
Anaerobic bacteria
D-amino acids and N-acetyl muramic acid is found in which of the following?
a) outer membrane of gram - bacteria
b) teichoic acid of gram + bacteria
c) peptidoglycan of gram - organisms
Peptidoglycan of gram - organisms
A patient has severe acute renal colic pain and microscopic hematuria. Which of the following is Most likely diagnosis?
a) cholelithiasis
b) urolithiasis
c) kidney tumor
d) choledocholithiasis
e) urinary bladder tumor
Urolithiasis
The presence of a granulomatous inflammation in gastrointestinal system of a patient is?
Crohn's Disease
Penicillin G is considered the 1st drug of choice in treating?
Neisseria Menigitidis
A patient takes an aspirin to relieve her toothache. Acetylsalicylate functions as a powerful anti-inflammatory because?
Aspirin inhibits the synthesis of prostaglandins
What concerns epithelioid cells seen in granulomatous inflammation?
Epithelioid cells are a result of the metamorphosis of macrophages from phagocytic cells to secretory cells
Each of the following DNA viruses encodes a DNA polymerase Except one.
a) Hepatitis B Virus
b) SV40
c) Adenovirus
d) Epstein Bar Virus
e) Pox Virus
SV40
Which of the following immune cells are important for targeting parasites?
a) Lymphocytes
b) Monocytes
c) Neutrophils
d) Eosinophils
e) Mast Cells
Eosinophils
Which of the following is NOT correct about interleukins?
a) IL-5 is produced by activated T helper cells and mast cells
b) IL-3 is secreted by T helper cells and mast cells
c) IL-8 is secreted by monocytes and macrophages
d) IL-10 is produced by bone mar
B IL-3 is screted by T helper cells and mast cells is incorrect
What virus causes Herpetic Whitlow?
Herpese synplex virus 1
HSV-1
Which of the following viruses has a naked icosahedral capsid and DNA genome?
a) adenovirus
b) Hepatitis B Virus (HBV)
c) Pox virus
d) Hepatitis A Virus (HAV)
e) VZV
Adenovirus has a naked icosahedral capsid and DNA genome
The presence of which of the following is a prominent characteristic of the Cryptococcus neoformans?
a) Teichoic acids
b) Golgi bodies
c) Peptidoglycan
d) Endoplasmic Reticulum
e) Carbohydrate Capsule
Carbohydrate capsule
What staphylococcal protein inhibits opsonization of IgG by interacting with the Fc fragment?
Protein A
What staphylococcal product acts to inhibit phagocytosis by attaching to the Fc portion of an IgG antibody?
Protein A
Which of the following is NOT a characteristic of reversible cell injury?
a) influx of Na+ into the cell
b) efflux of Ca++ from the cell
c) decrease in intracellular glycogen
d) influx of water into the cell
e) intracellular acidosis
Intracellular acidosis is NOT a characteristic of Reversible cell injury
What is an example of a type III hypersensitivity reaction?
Arthus' Reaction
Each of the following is a common feature of rabies and influenza Except one
a) Viral mRNAs have a 5' cap structure
b) isolated viral RNA is not infectious
c) the viral genome is ssRNA
d) the viral particles are enveloped
e) the viral genome is transcribe
The viral genome is transcribed in the cytoplasm of the host cell is incorrect
What is an enzyme that protects the CNS from free radical injury?
Superoxide Dismutase
Which of the following is true of cytokines?
a) Transforming Growth Factor beta suppresses secretion of inflammatory mediators and enhances B cells proliferation
b) T cell proliferation is influenced by TNF
c) Macrophages secrete TNF alpha
d) Bone marrow
Macrophages secrete TNF-alpha
Steroids such as prednisone and hydrocortisone act as acute anti-inflammatory drugs by inhibiting the?
Mobilization of arachidonic acid from phospholipids
What is responsible for the "toxic shock" syndrome of Streptococcus Pyogens and Staphylococcus aureus infection?
Super antigen
Porins are important for gram negative organisms for?
transport of molecules through the outer membrane
What is papillary cystadenoma lymphomatosera?
Benign epithelial thumor with prominent lymphoid tissue
Which of the following does NOT characterize an antiseptic and a disinfectant?
a) Disinfectants are chemical agents applied to inanimate surfaces and objects
b) Examples of antiseptics include 70% ethanol and 3% hydrogen peroxide and iodine
c) antiseptics
Antiseptics are more toxic than disinfectants is NOT true
A pathological finding that is diagnostic of ulcerative colitis is?
Crypt abcesses
Finding of yeast cells and chlamydospores in the oral mucosa and also the main fungal infection treated by dentists is caused by?
Candida Albicans
EBV is associated with each of the following Except one?
a) Burkitt's Lymphoma
b) Oral Hairy Leukoplakia
c) Infectious Mononucleosis
d) Nasopharyngeal Carcinoma
e) Kaposi's Sarcoma
Kaposi's Sarcoma is Not associated with EBV
B cell receptors differ from T cell receptors in tubules are lined by what?
B cell receptors have two arms while T cell receptors have only one
What is the minimum duration indicated by the manufacturers instructions to immerse non-heatable sterilization items such as rubber mixing bowl in a solution of 2% gluteraldehyde?
10 Hours
Each of the following is a property shared by filoviruses and hanta viruses Except one?
a) associated with hemorrhagic disease
b) negative stranded genomic RNA
c) segmented genomic RNA
d) enveloped viruses
e) encoded viral RNA transcriptase
Segmented genomic RNA is Not associated with filovirus and hantavirus
What has both chemotactic and anaphylatoxin activities in the complement cascade?
C5a
Each of the following is correct in regards to the complement system Except one?
a) C3a amd C5a are vasoconstrictors
b) C3a and C5a triggers degranulation of basophils and mast cells to release of histamine
c) C5b C6 C7 C8 C9 may assemble to form pores in
C3a and C5a are vasoconstrictors is Not true
Expression of adhesion molecules on endothelial cells is mediated by?
Interleukin-1
What disorder has the Philadelphia Chromosome?
Chronic Myelogenous Leukemia
Immunocompromised patient acquires a yeast infection through inflammation which led to pneumonia, the fungi leads to menigitis. What is the culprit?
Cryptococcus Neoformans
What tumor affecting chromaffin cells from producing sufficient levels of epinephrine and norepinephrine?
Pheochromocytoma
What term describes the transfer of genes or fragments of DNA between bacterium by a bacteriophage?
Transduction
What produces elementary bodies during its infectious cycle?
Chlamydia Trachomatis
Which of the following organisms is NOT likely to cause chronic adult periodontitis?
a) streptococci sanguis
b) porphymonas gingivalis
c) eichinella (not sure if I spelled this correctly)
d) Fusobacterium
e) Spirochetes
Streptococci Sanguis
A patient is fatigued with dry mouth and dry eyes. He has severe recurrent decay and early signs of periodontitis. Which of the following diseases does the patient most likely have?
a) osteoporosis
b) sjogren's syndrome
c) diabetes mellitus
d) scleroderma
Sjogren's syndrome
What is the MOST common tumor found in the salivary glands?
Pleomorphic Adenoma
Each of the following organisms can cross the placental barrier and infect the neonate in utero Except one?
a) syphilis
b) rubella
c) HSV-2
d) HIV
e) rotavirus
Rotavirus
What enzyme must RNA viruses have to be able to replicate?
RNA dependent RNA polymerase
The first line of defense and generally the earliest against a "new" viral infection is?
Natural Killer Cells
RSV differs from influenza in each of the following ways Except one?
a) RSV has stable antigens
b) RSV causes syncytia
c) RSV is larger
d) RSV has hemolysin
e) RSV is a ssRNA virus
RSV is a ssRNA viruse
RNA virus causing dyspnea. The viral envelope is composed of?
Lipoprotein
What is the best method to sterilize plastic instruments?
Ethylene Oxide
Where is the most likely site for a mucocoele?
Lower Lip
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