NBDE Microbiology/Pathology IV Flashcards

Terms Definitions
Although primary tumors of the heart are rare, what is the most common primary tumor of the heart in adults and is primarily located in the left atrium?
Myxoma
B cell proliferation for the secondary humoral immune response takes place in?
Germinal centers of the lymph nodes and of the spleen
Which of the following usually gains entry by inhalation of spores where it then invades the walls of blood vessels leading to necrosis, thrombosis and infarction in the lumen and is characteristic for broad nonseptate hyphae?
a) Blastomyces dermatidis
b)
Rhizopus spp.
The only acceptable plastic that can be used for steam sterilization or autoclave is?
Polypropylene
The induction of B-cells switching to IgE is stimulated by?
IL-4
Mutations, often inflicted by exposure to mutagens, viruses, or radiation, involve aberrant changes made to the genetic material that may affect the structure and function of its coded protein product. If a mutation alters a codon which encodes for an ami
Nonsense mutation
Which of the following is the only double stranded RNA virus?
a) Retrovirus
b) Togavirus
c) Orthomyxovirus
d) Reovirus
e) Rhabdovirus
Reovirus
Which antibiotics block the transfer of peptidoglycan subunits to the existing cell wall peptidoglycan?
Bacitracin
A bright field microscope is regularly used for cytological tests. When using bright field microscope, the resolution is dependent on the?
Numerical aperture and Wave length of the light
Where does respiration take place in bacteria?
Cytoplasmic membrane
A patient has recently undergone renal allograft transplantation. He complains that he urinates less frequently, his blood pressure has increased and that serum creatinine concentration has increased since his transplantation. Which of the following are r
T lymphocytes
Which of the following is a cytokine that is capable of decreasing inflammation?
a) IL-1
b) IL-6
c) IL-8
d) TGF-Beta
e) TNF
Transforming Growth Factor Beta
TGF-Beta
Which of the following bacteria can form endospores?
a) Clostridium and Staphylococcus
b) Clostridium and Bacillus
c) Mycoplasma and Bordetella
d) Streptococcus and Mycoplasma
e) Mycoplasma and Bacillus
Clostridium and Bacillus
Each of the following is a killed vaccine Except one.
a) Salk polio vaccine
b) Hepatitis B vaccine
c) Yellow fever vaccine
d) Thyphod vaccine
e) Cholera vaccine
Yellow fever vaccine
What molecule is necessary to present antigen to T helper cell?
MHC-class II
Negri bodies is diagnostic of?
Rabies
Alpha hemolytic streptococci is the major cause of?
Infective endocarditis
Which chromosomal abnormality is a cystic hygroma Most commonly associated with?
Turner's Syndrome
What makes a microscope a compound microscope?
It magnifies in two steps
Which of the following events occurs only in apoptosis and NOT necrosis?
a) Presence of Eosinophils
b) Peripheral aggregation of chromatin
c) Inflammation
d) Disaggregation of poly ribosomes
e) Karyolysis
Peripheral aggregation of chromatin
Your patient has swelling of the parotid glands. Which virus would show this clinical manifestation?
Mumps virus
Which of the following can NOT cause a congenital infecton?
a) Treponema pallidum
b) Toxoplasma gondii
c) Mumps
d) Cytomegalovirus
e) Rubella virus
Mumps
Which of the following is NOT a serious sequelae of an acute myocardial infarction?
a) Mitral valve dysfunction
b) Cardiac rupture
c) Ventricular aneurysm
d) Pericarditis
e) Mural thrombosis with embolus
Pericarditis
Rheumatic arthritis and Glomerular Nephritis are examples of what type of hypersensitivity reactions?
Type III
Which one of the following toxins is encoded on a plasmid?
a) Tetanus toxin
b) Shiga-like toxin
c) TSST-1
d) Cholera toxin
e) Pertussis toxin
Tetanus toxin
Syphilis, leprosy, trachoma, and tuberculosis are several human infections that reside in human tissues for long periods of time thus provoking a long drawn out battle between the microorganisms and the defenses of the host. This is called microbial?
Persistence
Which of the following conditions will NOT cause the formation of an aneurysm?
a) Syphilis
b) Atherosclerosis
c) Thromboangitis obliterans
d) Kawasaki's disease
e) Polyarteritis Nodosa
Thromboangitis obliterans
T/F
The presence of Koplik spots is an indication of a person infected with mumps. Koplik spots are small irregular red, white, and blue colored spots seen in the oral caity opposite to the maxillary molars?
The first statement is False, the second is True
Each of the following are correct statements about Escerichia coli and Pseudomonas aeruginosa Except one.
a) Escheria coli can ferment lactose while Pseudomonas aeruginosa cannot
b) Pseudomonas aeruginosa has pertrichous flagella while Escherichia coli ha
Pseudomonas aeruginosa has pertrichous flagella while Escherichia coli has polar flagella
What is the genetic cause for the most common lysosomal storage disease causing mental retardation?
Tay-Sachs disease
The relative percent 3-year survival from common neoplasms is the highest for?
a) Ovary
b) Breast
c) Thyroid
d) Pancreas
e) Colon
Thyroid
American Burkitt's lymphoma is?
Isolated jaw involvement is more common in African than American Burkitt's lymphoma
Aphthous ulcers typically do NOT occur in the
a) buccal mucosa
b) gingiva
c) soft palate
d) lateral border of the tongue
e) floor of mouth
Gingiva
Large numbers of inflammatory cells such as lymphocytes are found in the loose connective tissue of the?
GI tract and Respiratory system
Collagen synthesis as measured by prolyl hydroxylase activity is?
Significantly higher in keloids
A patient contracts polio and is prescribed a polio vaccine to decrease the polio infection. The difference of the Sabin polio vaccine compared to the Salk polio vaccine is?
Sabin polio vaccine induces cytotoxic T cells whereas Salk polio vaccine does not
Which of the following can NOT cause chronic lymphadenitis?
a) Dilantin (diphenylhydantoin)
b) HIV infection
c) Rheumatoid arthritis
d) Rubeola
e) Syphilis
Rubeola
The mode of action of diphtheria toxin is through?
Inactivation of elongation factor-2
What describes viruses?
Viruses are obligate intracellular parasites
The patient presents with severe epigastric pain radiating to his back. He also claims he is a heavy alcohol drinker. The most likely diagnosis of the patient is?
Acute pancreatits
The dentist speculates that the patient presents with Sjogrens syndrome. What type of tumors arise from the onset of Sjogren's syndrome, Hashimoto's thyroiditis, or Helicobacter pylori infection of the stomach?
Mucosa-associated lymphoid tissue (MALT Lymphoma)
Parkinson's disease is the result of neuronal deficiency in the?
Substatia Nigra
The patient is taking medications such as Fosamax to help reverse bone loss. Serum alkaline phosphatase levels are elevated in each of the following conditions Except one.
a) Osteitis fibrosa cystica
b) Osteoporosis
c) Rickets
d) Osteosarcoma
e) Pagets di
Osteoporosis
If the influenza A virus isolated in 2007 is H3N2 and those isolated in 2006 are also H3N2 but slightly different from 2007 strain, therefore requiring a new viral strain for the 2007 vaccine, this would be an example of?
Antigenic Drift
During the medical history, the sexually active patient reports to the dentist that she contracted with a urinary tract infection last month. Which of the following Staphylococci is Most responsible from causing this urinary tract infection?
a) Staphyloco
Staphylococcus Saprophyticus
The dentist examine the tongue of the patient and spots oral hairy leukoplakia. The lesions seen in oral hairy leukoplakia are NOT
a) characterized by little or no associated inflammation
b) characterized by epithelial dysplasia
c) most commonly seen on t
Characterized by epithelial dysplasia
Because the patient is sexually active and has unprotected sex, the patient believes she might be infected with Hepatitis B. She has not been vaccinated and wishes to take a blood test. Since the patient may be in the window period, clearance of which of
HBsAg
The patient also opts to take an HIV test. Which of the following is NOT characteristic of infections caused by HIV?
a) HIV infects monocytes
b) CD8 to CD4 is reduced
c) GP120 protein on the viral envelope binds to CD4 protein receptor on target cell
d) H
CD8 to CD4 ratio is reduced
The patient recently overcame a Salmonella infection from eating raw eggs. However, the patient may be in a carrier state as Salmonella organisms have been known to persist for years in which of the following organisms?
a) Liver
b) Spleen
c) Pancreas
d) K
Gall Bladder
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