Nursing 117 Section I Unit VI Flashcards

Terms Definitions
Absorption
The act of taking up or in by specific chemical or molecular action; especially the passage of liquids or other substances through a surface of the body into body fluids and tissues, as in the absorption of the end products of digestion into the villi that line the intestine
Adverse drug event (ADE)
An injury resulting from medical intervention related to a drug
Adverse effect
Result of drug or other therapy in addition to or in extension of the desired therapeutic effect; usually but not necessarily, connoting an undesirable effect.
Adverse Reaction
Any undesirable or unwanted consequence of a preventive, diagnostic, or therapeutic procedure or regimen
Affinity
Attraction; a tendency to seek out or unite with another object or substance
Agonist
A substance (e.g. a drug, hormone or neurotransmitter) that binds with a cell receptor to initiate a physiological response similar to that produced by the natural neurotransmitter or hormone
Allergies
Abnormal reactions of the immune system that occur in response to otherwise harmless substances.
Analgesic
A medication capable of reducing or eliminating pain
Antagonist
A substance (e.g. a drug, hormone or neurotransmitter) that depresses the action of an agonist or binds to a cell receptor without eliciting a physiological response (e.g. excitation or inhibition).
Bioavailability
The degree to which a drug or other substance becomes available to the target tissue after administration
Biotransformation
The chemical and physical changes produced in drugs after they enter the body
Classification
The systematic arrangement of similar entities on the basis of certain differing characteristics.
Compatibility
The formation of a stable chemical or biochemical system, specifically in medication, so that two or more drugs can be administered at the same time without producing undesired side effects or without canceling or affecting the therapeutic effects of the others.
Controlled Substance
A drug or chemical substance whose possession and use are regulated under the Controlled Substances Act
Diluent
A substance, generally a fluid, that makes a solution or mixture less concentrated, less viscous, or more liquid
Dissolution
The dissolving of chemical substances into a homogenous solution.
Distribution
The location of medications in various organs and tissues after administration.
Drug Interactions
Pharmacologic result, either desirable or undesirable, of drugs interacting with other drugs.
Drug solubility
Solubility is the property of a solid, liquid, or gaseous chemical substance called solute to dissolve in a solid, liquid, or gaseous solvent to form a homogeneous solution of the solute in the solvent.
Duration of Action
Therapeutics The length of time that a particular drug is effective
Efficacy
The degree to which an intervention accomplishes the desired or projected outcomes.
Excretion
The act or process of discharging waste matter from the blood, tissues, or organs.
Free Drug
Unbound drug Pharmacology An active drug or other compound that is not bound to a carrier protein–eg, albumin or alpha-1-acid glycoprotein
Generic name
a nonproprietary designation for any compound used as a drug, established by negotiation between their manufacturers and a council sponsored jointly by the American Medical Association, American Pharmaceutical Association, and United States Pharmacopeial Convention.
Half-life
The amount of time required to reduce a drug level to half of its initial value. Usually the term refers to time necessary to reduce the plasma value to half of its initial value. After five half-lives, 97% of a single drug dose will be eliminated
Hives (uticaria)
A vascular reaction of the upper dermis marked by transient appearance of slightly elevated patches (wheals) which are redder or paler than the surrounding skin and often attended by severe itching.
Hospital formulary
A continually revised compilation of approved pharmaceuticals, plus important ancillary information, which reflects the current clinical judgment of the institution's medical staff.
Iatrogenic
Resulting from the activity of physicians; said of any adverse condition in a patient resulting from treatment by a physician or surgeon.
Idiosycrasy
A peculiarity of physical or mental constitution or temperament
Indications
A sign or circumstance that points to or shows the cause, treatment, or some other aspect of a disease.
Intradermal
Within or between the layers of the skin.
Intramuscular
Within a muscle
Intravenous
Within or administered into a vein.
KVO
keep vein open.
Loading dose
a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
Macrodrop
Maintenance dose
Medication administration
Record (MAR)
Microdrop/Microdrip
Metabolism
Mechanism of action
Nursing implications
Onset of Action
Quality Improvement
Peak
Peak of Action
Pharmacokinetics
Physician's desk reference (PDR)
Protein binding
Prototype
Pyxis
Receptor
Side effect
Solute
Solution
Subcutaneous
Sublingual
Synergism
Therapeutic index
TKO
Tolerance
Topical
Trade name
Trough
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