Allergan - Lastacaft Flashcards

Lastacaft
Terms Definitions
In clinical studies what were the most frequently reported non-ocular adverse reactions occurring in less than 3% of patients?
Nasopharyngitis, headache, and influenza
In clinical studies what were the most frequently reported ocular adverse reactions occurring in less than 4% of patients?
Eye irritation, burning and/or stinging, Eye redness, and Eye pruritus
Lastacaft can be used in patients from what age on?
Two and over
What is the dosage of Lastacaft?
.25%
How is Lastacaft dosed?
One drop in each Eye once daily
What are the three warnings and precautions in the product label?
Contamination of tips and solution, topical ophthalmic use only, and contact lens use
What preservative is in the Lastacaft?
BAK .005%
What is lastacafts mechanism of action?
H one receptor antagonist inhibitor of the release of histamine from mast cells, It decreases chemotaxis and inhibition of eosinophill activation has also been demonstrated
What is the amounts and size of the bottle of Lastacaft
3ml in 5ml bottle
What is lastacafts indication?
The prevention of itching associated with allergic conjunctivitis
What is the pregnancy category of Lastacaft?
B
What's is the generic name of Lastacaft?
Alcaftadine
How many patients were studied in the efficacy studies?
274 patients
How many patients were any safety studies?
909
Based on ocular allergen challenge at three minutes what percent of patients achieved results?
97%
Based on ocular allergen challenge post dosing at 16 hours for the percent of patients reduced ocular itching?
87%
What are the four steps to the Allergan challenge question
1 exposure to Allergan look for response 2 read exposure Allergan 3 duration of action 3, 5 and 7 minutes (16hr) 4 onset of action (3 min)
How long should you wait to put in your contact lenses after instilling Lastacaft?
10 minutes
What is the osmolarity of Lastacaft?
290
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