Nursing pharmacology: Respiratory Drug Name Flashcards

Terms Definitions
beractant (Survanta)
SURFACTANTS
aminophylline
oxtriphylline
theophylline**
BRONCHODILATOR Drugs
xanthine Derivatives: Phosphodiesterase Inhibitors
fluticasone (Flonase)
DECONGESTANTS
Intranasal Steroids
colfosceril (Exosurf Neonatal)
SURFACTANTS
oxymetazoline (Afrin)
nasal inhalation decongestant
class of
loratadine (Claritin)
H1 antihistamine
astemizole (Hismanal)
ANTIHISTAMINE
H1 Receptor Antagonists
naphazoline (Privine)
DECONGESTANTS
Adrenergic Nasal decongestant
loratadine (Claritin)
ANTIHISTAMINE
H1 Receptor Antagonists
desoxyephedrine (Vicks Inhaler)
DECONGESTANTS
Inhalation (OTC)
oxymethazoline (Afrin)
DECONGESTANTS
Adrenergic Nasal decongestant
beclomethasone (Beclovent)**
CORTICOSTEROIDS
also antiinflammatory agents
terbutaline (Brethine)
BRONCHODILATOR Drugs
Sympathomimetic Drug
Beta 2 receptor drug
diphenhydramine (Benadryl)**
COUGH SUPRESSANTS
Nonopioid Antitussive Drug
cromolyn (Intal)**
PROPHYLACTIC ANTIASTHMATIC Drugs
acetylcysteine (Mucomyst)
COUGH SUPRESSANTS
Mucolytic Drugs
phenylephrine
(Neo-Synephrine, Sinex)
nasal inhalation decongestant
cydrocodone bitartrate**
COUGH SUPRESSANTS
Opioid Antitussive Drugs
isoproterenol solution (Isuprel)
BRONCHODILATOR Drugs
Sympathomimetic Drug
Nonselective Beta-Adrenergic Drugs
codeine phosphate**
COUGH SUPRESSANTS
Opioid Antitussive Drugs
atropine
D. Drugs that Antagonize Bronchial Secretion
Anticholinergic agents
Class and Mechanism of
Guaifenesin
(Robitussin, Guiatuss, Humibid)
-Expectorant
-Reflex stimulation:
loosening and thinning of the respiratory tract;
-secretions occurs in response to an irritation of the GI tract produced by the drug.
Class of cetirizine (Zyrtec)
and indication.
Anticholinergic: H1 antihistamine
treatment of year round allergies as well as seasonal allergies.
Side effects of
Guaifenesin
(Robitussin, Guiatuss, Humibid)
1. stomach upset
2. nausea
List contraindications for sympathomimetic bronchodilators.
Client on sympathomimetic bronchodilators should not use:
1. MAO inhibitors
2. tricyclic antidepressants
3. antihisamine
4. sodium levothyroxine
Side effects/ Adverse reaction for nasal decongestants.
Adrenergic:
1. nervousness
2. insomnia
3. palpitation
4. tremor
intranasal steroids:
1. mucosal irritaion
2. mucosal dryness
List side effects of Xanthine.
1. tachycardia
2. dysrhythmias
3. diuresis
Name the most commonly used mucolytic agent.
acetylcysteine (Mucomyst)
side effects of:
cromolyn sodium and nedicromil sodium
1. cough
2. bronchospasm
Name commonly used intranasal steroids.
1. Beconase**
2. Flonase**
3. Vancenase
4. Pullmicort
5. Rhinocort
6. Nasacort
7. nasalide
8. Turbuhaler
mechanism of corticosteroid
produce an antiinflammatory effects by decrease the number of inflammatory cells in the respiratory tract, which leads to decrease bronchoconstriction.
Side effects of zafirlukast (Acculate)
1. headache
2. nausea
3. diarrhea
List the three non-narcotic antitussive agents.
1. benzonatate (Tessalon)
2. dextromethorphan HBr* (benylin DM, Robitussin DM)
3. diphenhydramine HCl (Benedryl)
Interaction for nonnarcotic antitussin:
dextromethorphan HBr
(Benylin DM, Robitussin DM)
dextromethorphan may potentiate the serotonergic effects of MAOIs and thus concurrent administration is contraindicated.
What expectorant is not approved by the FDA?
Ammonium Chloride
Contraindications for
adrenergic nasal decongestant.
1. drug allergy
(Adrenergic drugs)
2. narrow-angle-glaucoma
3. uncontrolled cardiovascular disease
4. diabetes
5. thyroid dysfunction
6. prostatitis
guiafenesin and codeine (Robitussin A-C)**
COUGH SUPRESSANTS
Opioid Antitussive Drugs
Side effects of leukotriene receptor antagonists.
1. headache
2. drowsiness
3. fatique
4. GI diturbances
5. liver dysfunction
Usage of Ipecac syrup
1. low dosage (0.25-1) expectorant
2. high dosage (15ml) potent emetic
Indications of leukotriene receptor antagonists
1. chronic stable asthma
2. exercise-induced asthma attacks
3. allergies
**not for acute asthma attack**
List contraindication to Xanthine bronchodilator drugs
1. drug allergy
2. cardiac dysrhythmias
3. seizure
4. hyperthyroidism
5. peptic ulcers
Mechanism of
benzonatate (Tessalon)
acts by providing local anesthetic action, which impairs sensation of the stretch receptors located in the respiratory tract, thereby interfering with the cough reflex.
Mechanism of
dextromethorphan HBr
(Benylin DM, Robitussin DM)
acts on the cough center inthe medulla, but does not cause respiratory depression, analgesia, or dependence.
Class and Mechanism of
Terpin hydrate
-expectorant
-act by stimulating the secretory glands directly to increase natural respiratory tract secretions.
Name 4 example of Xanthine bronchodilator drugs.
*generic name ends with "phylline"*
1. aminophylline
2. dyphylline
3. oxtriphylline
4. theophylline
List drugs that will interact with Xanthine bronchodilator drugs
1. allopurinol
2. cimetidine
3. erythromycin
4. flu vaccine
5. contraceptives
list the indications for Xanthine bronchodilator drugs
1. acute asthma
2. chronic bronchitis
3. emphysema
4. COPD
Name the 3 narcotic antitussive agents.
1. codine phosphate
2. hydrocodone bitartrate
2. guaifenesin and codine (Robitussin A-C)
What should clients taking sympathomimetic bronchodilators be monitored for?
1. changes in cardiac function
2. changes in BP
3. CNS stimulations such as insomnia, nervousness, anxiety, tremor, and GI disturbances.
When is cromolyn administer by orally?
in the treatment of mastocytosis becuse cromolyn dose exert a local action in the mast cells w/i the GI tract.
What are the overall effects of histamine?
1. contriction of smooth muscle
(especially in the stomach and lungs).
2. Increase in body secretions.
3. vasodilation
4. Increase in capilary permeability.
5. Drop in BP
6. Edema
What are the contraindications for expectorants?
1. drug allergy
2. hyperkalemia
(for potassium contanning expectorant)
These three agents are contraindicated in what types of clients? trimeprazine, methdilazine, promethazine
1. comatose
2. sensitive to phenothiazine drugs
3. hepatic disorders
4. CNS depression (due to barbiturates, narcotic analgesics, or alcohol)
What is Cromolyn Sodium
drug use in the tratment of allergic rhinitis.
Antihistomine should be use in caution in clients with..
1. brochial asthma
2. increase intraoccular pressure
3. prostatic hypertrophy
4. elderly
What are the adverse effects associated with
acetylcysteine (Mucomyst)
development of bronchospasm as a result of the aerosol administration.
What is the mechanism of adrenergic nasal decongestant agents?
-shrink engorged nasal mucosal membranes and relieve nasal stuffiness by stimulating the Alpha1-adrenergic nerve receptors in vascular smooth muscles.
-Thereby constricting the small arterioles that supply the structures of the upper respiratory tract, primarily the blood vessle surrounding the nasal sinuses.
-reduces flow and allows for drainage.
List the side effects of narcotic antitussive:
Codine & Hydrocodone
1. sedation
2. nausea
3. vomiting
4. lightheadedness
5. constipation
Name the 4 H2 antagonists or H2 blockers.
1. cimetidine
2. ranitidine
3. famotidine
4. nizatidine
Decribe the mechanism of brochodilation caused by sympathomimetic agents.
when the Beta 2 receptors of mast cells is stimulated by sympathomimetic agents, there is an increase in the formation of cyclic AMP. cAMP is associated with smooth muscle relaxation and bronchodilation.
Sympathomimetic agent => B2 => cAMP => bronchodilation.
What should the client who are taking Xanthine bronchodilator drugs be monitored for?
stimulation of CNS:
1. insomnia
2. hyperexcitability
3. potential for seizure activity
What are the methods of administration of
acetylcysteine (Mucomyst)
1. nebulization: tent, facemask, or mouthpiece
2. direct instillation of the solution into an intratracheal catheter.
Describe the mecahinism of Xanthine Bronchodilators.
The agent interfere with the action of phosphodiesterase, an enzyme that breaks down cyclic AMP to inactive product. An increase in intracellular cAMP leads to brochodilation.
Xanthine x=> PhDR x=> cAMP => bronchodilation
What are the adverse effects of
ipratropium bromine(Atrovent)
1. dry mouth or throat
2. GI distress
3. headache
4. coughing
5. anxiety
What is that advange of saline nose drop?
1. non habit forming
2. can be use more often during the day than most decongestants
3. inexpensive
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