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Major Histocompatibility Complex (MHC) Explained Quiz

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1. What is the primary role of the Major Histocompatibility Complex (MHC) in the immune system?

2. MHC class I molecules present antigens to which type of cells?

3. Which of the following is NOT a function of MHC class II molecules?

4. Which locus encodes the MHC class I molecules in humans?

5. What differentiates MHC class I and class II molecules in terms of antigen presentation?

6. What is the significance of polymorphism in MHC molecules?

7. Which genes are NOT part of the MHC in humans?

8. How do MHC class II molecules acquire their peptide cargo?

9. In the context of transplantation, why is matching MHC molecules between donor and recipient important?

10. Which cells are the primary presenters of antigens via MHC class II molecules?