apoptosis
programmed cell death
benign
describing a tumor that will not spread and thus is not cancerous
cancer
disease that results from an overgrowth of cells that survive and divide abnormally
cancer subtype
division of a type of cancer based on the properties of the malignant cells
carcinogen
substance that causes cancer
chemotherapy
use of chemical drugs to treat disease, usually cancer
cytotoxic
quality of something that poisons living cells
germ cell
reproductive cell, such as a sperm or an egg
human epidermal growth factor receptor 2 (HER2)
receptor that is involved in signaling for apoptosis
malignant
describing a tumor that invades surrounding tissues and thus is cancerous
metastasis
condition in which some cells from a tumor come loose and enter the bloodstream or lymphatic vessels, thus causing the cancer to spread from its origin
monoclonal antibody
protein that counteracts a specific antigen that is produced from a single cell or from clones of a single cell
oncogene
gene that can cause cancer if it undergoes certain mutations
proto-oncogene
corresponding normal version of the oncogene without the mutation
somatic cell
body cell
surface receptor
protein found on the surface of the cell to which substances can bind
tamoxifen
cancer drug that is metabolized into molecules that bind to estrogen receptors
trastuzumab
monoclonal antibody that targets HER2
tumor
mass resulting from an overgrowth of cells
tumor suppressor gene
normal version of a loss-of-function gene that leads to cancer