Cancer

Vocabulary

apoptosis

programmed cell death

benign

describing a tumor that will not spread and thus is not cancerous

cancer

disease that results from an overgrowth of cells that survive and divide abnormally

cancer subtype

division of a type of cancer based on the properties of the malignant cells

carcinogen

substance that causes cancer

chemotherapy

use of chemical drugs to treat disease, usually cancer

cytotoxic

quality of something that poisons living cells

germ cell

reproductive cell, such as a sperm or an egg

human epidermal growth factor receptor 2 (HER2)

receptor that is involved in signaling for apoptosis

malignant

describing a tumor that invades surrounding tissues and thus is cancerous

metastasis

condition in which some cells from a tumor come loose and enter the bloodstream or lymphatic vessels, thus causing the cancer to spread from its origin

monoclonal antibody

protein that counteracts a specific antigen that is produced from a single cell or from clones of a single cell

oncogene

gene that can cause cancer if it undergoes certain mutations

proto-oncogene

corresponding normal version of the oncogene without the mutation

somatic cell

body cell

surface receptor

protein found on the surface of the cell to which substances can bind

tamoxifen

cancer drug that is metabolized into molecules that bind to estrogen receptors

trastuzumab

monoclonal antibody that targets HER2

tumor

mass resulting from an overgrowth of cells

tumor suppressor gene

normal version of a loss-of-function gene that leads to cancer