anaphase
phase of mitosis in which sister chromatids separate and are pulled to the opposite poles of the cell
aneuploidy
abnormal number of copies of a particular chromosome
apoptosis
programmed death of cell, including destruction of its DNA and organelles
astral microtubule
spindle fiber that attaches the centrosome to the cell membrane
binary fission
process by which prokaryotic cells divide; asexual reproduction
cell cycle
life of a cell, from its beginning to the time when it divides to produce a new cell
cell division
process by which one cell divides and becomes two new cells
cell equator
imaginary line in the center of a cell during mitosis, along which sister chromatids align
cell plate
partition that forms along the midline of a dividing plant cell
cell-cycle control system
series of checkpoints directed by chemical signals in a cell that regulate cell growth and division
centromere
point on a chromosome that attaches to the spindle fibers with a kinetochore during cell division and at which sister chromatids are attached
centrosome
structure in the cytoplasm of animal cells that coordinates the formation of microtubules, which allows cell division to proceed during reproduction
chromatid
one of two identical halves of a replicated chromosome
cleavage furrow
indentation in an animal cell along which cytokinesis occurs
cohesin
protein that helps bind sister chromatids together at the centromere
condensin
protein that helps condense DNA into chromosomes during prophase of mitosis
cyclin
regulatory molecule that functions as a gatekeeper, along with cyclase-dependent kinases (Cdks), to move a cell past checkpoints in the cell cycle
cyclin-dependent kinase (Cdk)
regulatory molecule (usually a protein) that functions as a gatekeeper, along with cyclins, to move a cell past checkpoints in the cell cycle
cytokinesis
pinching off of the cytoplasm to form two new cells at the end of mitosis
interphase
collectively the G1, S, and G2 phases of mitosis, in which a cell grows, replicates its DNA, and grows again
interpolar microtubule
spindle fiber that extends from one centrosome to the other across the cell equator
kinetochore
group of proteins bound at the centromere to which the spindle fibers attach
metaphase
phase of mitosis in which the sister chromatids line up along the cell equator
mitosis
process of cell division that results in two cells that are genetic clones of the parent cell
mitotic spindle
bundle of spindle fibers attached at one end to the centrosome
origin of replication
place on a chromosome where DNA replication begins
polyploid
having more than two paired sets of chromosomes
prometaphase
phase of mitosis in which the nuclear membrane breaks down and spindle fibers attach to the centromere
prophase
phase of mitosis in which sister chromatids condense, the mitotic spindle begins to form, and centrosomes segregate to opposite poles
vesicle
small piece of cell membrane used to transport materials within a cell