animal reservoir
organism in which a pathogen can replicate, often without causing disease, and that serves as a source of infection for humans
apicomplexan
single-celled parasitic protozoan with a specialized set of organelles, vacuoles, and microtubules called the apical complex
bacteremia
presence of bacteria in the blood
bubonic plague
form of plague in which infection by the virulent bacterium Yersinia pestis spreads through the lymphatic vessels and the lymph nodes swell, forming large, colored nodules called buboes
cardiovascular system
system (composed of the heart, blood vessels, and blood) that pumps and transports blood throughout the body, delivering oxygen, nutrients, and hormones while removing carbon dioxide and other metabolic wastes
causative agent
biological pathogen or chemical toxin that causes a disease
endocarditis
inflammation of the inner lining of the heart chambers and valves (the endocardium), which can disrupt the heart's rhythm and lead to death
lymphatic system
network of specialized tissues, glands (nodes), and vessels that return fluid to the bloodstream while storing and circulating cells and fluids involved in immune responses
plague
infectious disease caused by the bacillus bacterium Yersinia pestis. It has three clinical forms: bubonic, pneumonic, and septicemic.
pneumonic plague
form of plague in which the lungs are heavily invaded/infected by the virulent bacterium Yersinia pestis
sepsis
condition in which an infection results in a system-wide inflammatory response, which causes severe damage to the tissues and can result in death if not treated immediately
septic shock
severe inflammatory response due to a specific type of sepsis that is stimulated by lipopolysaccharide (LPS), a component that is unique to the cell walls of gram-negative bacteria
septicemic plague
form of plague in which the bloodstream is so severely infected by the virulent bacterium Yersinia pestis that tiny clots form throughout the body, potentially causing death by blocking blood vessels and causing organ failure
systemic infection
infection that spans multiple tissue types
viremia
presence of viruses in the blood