ABO blood grouping
most common characterization of blood based on the presence or absence of A and B antigens on the surface of red blood cells
allele
version of a gene
allergen
antigen with an environmental origin and capacity to elicit a type I hypersensitivity response with immunoglobulin E (IgE)
allergic rhinitis
type I hypersensitivity response in which plant pollen acts as the allergen
alloimmunity
immune response in which the immune system produces antibodies against antigens from another individual of the same species
anaphylaxis
severe and rapidly developing allergic reaction that may involve eczema, swelling in the face or throat, drops in blood pressure, and digestive upset
atopy
genetic predisposition to developing type I hypersensitivities
autoantibody
antibody that recognizes antigens on cells of the same individual that creates the antibodies
autograft
tissue or organ that is transferred to a new position within the body of the same individual
autoimmunity
immune response that is mounted against the host's own body cells and tissues
eczema
disease characterized by skin swelling and typically involves an itchy, inflamed skin rash
hemolytic disease of the newborn (HDN)
lysis of fetal and newborn red blood cells that results from an influx of maternal antibodies into the fetus that target Rh antigens on the surface of the red blood cells
histamine
small, organic, inflammation-mediating molecule that increases blood flow by causing vasodilation and promotes swelling by increasing local capillary permeability
immune complex
molecule formed from the binding of an antibody to an antigen
immunopathology
branch of pathology dealing with the immune system and its response to disease and infection
leukotriene
any of a family of related inflammation-mediating molecules released by phagocytes, basophils, and injured cells to attract neutrophils from the blood to sites of infection
primary immunodeficiency
failure (due to genetic or developmental defects) of the immune system to adequately protect the body from infections and other health problems
prostaglandin
any of a family of pro-inflammatory lipids released by granulocytic leukocytes, which causes pain by promoting vasodilation
Rh factor
one of a group of antigens typically found on red blood cells that yields an Rh-positive blood type. A person lacking Rh antigens on their red blood cells is Rh-negative.
secondary immunodeficiency
failure (due to pathogens, poor nutrition, or immunosuppressive therapies) of the immune system to adequately protect the body from infections and other health problems
serum sickness
type III hypersensitivity reaction forming antigen-antibody complexes with proteins in medicines or antisera, thus causing fever, malaise, hives, itching, joint pain, rash, or lymph node swelling
xenograft
tissue or organ transplant from a donor species that is different from the recipient species