# Amines

## Vocabulary

### amine

organic compound that is a derivative of ammonia (NH3), where one or more hydrogen atoms are replaced by alkyl or aryl units (R), forming ${\rm{N{-}R}}$ single bonds

### ammonium cation

cation with the chemical formula NH4+ that is formed from the protonation of ammonia (NH3)

### chiral molecule

molecule that does not have a plane of symmetry whose isomers cannot be interconverted by rotation or reflection

### nitrogen inversion

process in which the lone pair on the nitrogen rapidly inverts so that the molecule is not chiral

### primary amine

organic compound that is a derivative of ammonia (NH3), where an alkyl or aryl unit (R) replaces one hydrogen atom, forming an ${\rm{N{-}R}}$ single bond

### quaternary amine

organic compound that is a derivative of ammonia (NH3), where alkyl or aryl units (R) replace three hydrogen atoms and the lone pair of electrons

### resolving agent

chiral compound added to a racemic mixture to form diastereomeric salts. The salts are separated and separately converted back into the separate R and S enantiomers of the mixture.

### secondary amine

organic compound that is a derivative of ammonia (NH3), where alkyl or aryl units (R) replace two hydrogen atoms, forming ${\rm{N{-}R}}$ single bonds

### stereogenic center

single tetrahedral atom with four different groups

### tertiary amine

organic compound that is a derivative of ammonia (NH3), where alkyl or aryl units (R) replace three hydrogen atoms, forming ${\rm{N{-}R}}$ single bonds