Reactions of Carboxylic Acid Derivatives

Vocabulary

acid anhydride

organic compound that contains two carbonyl groups (C=O{\rm {C{=} O}}) bound to the same oxygen atom with (RCO)2O stoichiometry

acid halide

organic compound that contains a carbonyl group (C=O{\rm {C{=}O}}) bound to one alkyl (R{-}{\rm {R}}) fragment and one halogen atom, with RC(=O)X{\rm{RC({=}O)X}} or RCOX{\rm R{-}{COX}} stoichiometry

aldehyde

organic compound that contains a carbonyl group (C=O{\rm{C{=}O}}) bound to one alkyl (R{-}{\rm {R}} ) fragment and one hydrogen atom, with RC(=O)H {\rm{RC{(=}O)H}} or RCHO {\rm{R{-}CHO}} stoichiometry

amide

organic compound that contains a carbonyl (C=O{\rm{C{=}O}}) linked to nitrogen atoms through a CN {\rm{C{-}N}} bond. It has a general RC(=O)NRR {\rm{RC ({=}O)NRR}'} stoichiometry.

benzylic carbon

carbon that is adjacent to a benzene ring

carbonation

reaction that results in the addition of a carbon to a structure

cyanohydrin

compound that contains a carbon that is bonded to a hydroxyl group (OH{-}{\rm{OH}}) and a cyano group (CN{\rm{C{\equiv}N}}) on the same carbon

dehydration

loss of a water molecule

ester

organic compound that contains a carboxyl unit in which a hydroxyl group is replaced by an alkyl or aryl group, giving it RC(=O)OR{ \rm{R{-}C({=}O)OR}'} or RCOOR{\rm {R{-}COOR}'} stoichiometry

Grignard reagent

reagent that has the formula RMgX{\rm{R{-}MgX}}, where the halogen may be Cl{-}{\rm{Cl}} , Br{-}{\rm{Br}} , or I{-}{\rm {I}}

hydrolysis

addition of water to a molecule to cause a covalent bond to break

ketone

organic compound that contains a carbonyl group (C=O{\rm {C{=}O}}) bound to two alkyl (R{-}{\rm {R}}) fragments (which can be the same, R and R, or different, R and R′) with RC(=O)R{\rm{RC({=}O) R}'} or RCOR ′ stoichiometry

nitrile

organic compound that has a carbon triple bonded to a nitrogen with RCN stoichiometry

organometallic reaction

nucleophilic addition reaction with an organometallic reagent

ozonolysis

cleavage of an alkene, alkyne, or azo group with ozone

primary amide

organic compound that contains a carbonyl (C=O{\rm{C{=}O}}) linked to a nitrogen atom that has two hydrogen atoms (NH2)

transesterification

reaction that trades the R{-}{\rm {R}} group of the ester with an R{-}{\rm {R}} group of an alcohol