Alkanes & Cycloalkanes
Professor William Tam & Dr. Phillis
Ch. 4 Chang
About The Authors
These Powerpoint Lecture Slides were created and prepared by
Professor William Tam and his wife Dr. Phillis Chang
Biochemistry 461, Spring 2014
Final Exam W
1. When comparing DNA polymerases I, II, and III from E. Coli, what feature distinguishes DNA
Polymerase I from the rest?
Pol I is the larg
Dr. John C. Shimko
Jennings Hall 155
Tuesdays and Thursdays 11:10 12:30 AM
Contact Information and Office Hours
Dr. John C. Shimko
707 Biol. Sciences Building
Biochemistry I - Second Exam 2004
Section A (21 pts): (3 pts/question). Circle the letter corresponding to the best answer.
1. One ligand binds more tightly to a protein than another ligand if:
a) its KA (KEQ) is lower than the other l
Spring 2004 BCHS 3304 Final Exam Review1). The TR transition of hemoglobin upon binding of oxygen to the heme has been thoroughly
investigated. On a thermodynamic level, this TR transition can be described as (primarily) an
enthalpically driven process. W
A. Water (H2O) - 60-80% of cells
heat capacity - ability to store lots of heat
heat of vaporization - lots of heat to evaporate
polarity/solvency - ability to dissolve reactants
salts and large m
The study of chemical constituents of living organisms.
Organic Molecules - Materials that are formed in the metabolism of living things.
The wide range of Organic compounds in living organisms may be conventionally divided into 5 major
Carbohydrates are normally the first classification of compounds to be discussed which fall
within the realm of Biochemistry. All biological systems are run on chemical reactions: some are
easy to see, such as the iron io
Protein Function !
Protein - Ligand Interactions"
Ligand: any molecule that binds to a protein!
Usually reversible and transient
"Lehninger Principles of Biochemistry, 4th & 5th Ed"
DNA and RNA structure and behavior will be covered heavily in
We will go quickly through this material, to learn the background
required to understand basic bioche
Protein Folding and Dynamics!
How does a protein fold?!
Levinthals paradox (Cyrus Levinthal): !
Can a protein fold through a random, sequential search pattern?!
Every residue in a protein has two torsion angles (!,
20 Common or Natural AAs
A Ala Alanine
F Phe Phenylalanine
K Lys Lysine
C Cys Cysteine
G Gly Glycine
P Pro Proline
L Leu Leucine
N + COOH2
Q Gln Glutamine
D Asp Aspartate
H His Histidi