PART 1 - (10 Points)
Langer and Vacanti describe 3 general approaches for tissue engineering, isolated cells or
cell substitutes, tissue-inducing substances, and cells + matrix. Describe one example of
1. (10 Points) For the following process there are no reactions, there is no accumulation,
and the only components in the system are A, B, and C.
The composition of stream is in mass fractions and the total flow rate is in mg/s.
5 March 2014 Name _
Problem 1 (10 Points)
Write the rate law for the specified chemical species corresponding to the following mechanisms.
Assume each system is closed and constant volume. For each mechanism, use k 1 for the forward reacti
6 March 2013
1. (10 Points) Writing rate laws for elementary reactions.
A. Consider the elementary reaction A products. The rate law of this reaction is kCA. Often the rate law of
this reaction is written as dCA/dt = - kCA. To do
1. (15 points) From the three articles you read on tissue engineering of blood vessels listed below, pick one, circle it, and describe
how the tissue-engineered blood vessels were created in the paper.
Paper 1: A completely biolo
26 April 2012
1. (5 Points). If the following equation is correct, what are the dimensions of z?
2. (15 Points) During a drive from Lancaster to Philly in a snowstorm, your instructor noticed that when driving at
31 May 2010
1. Review the "guide to reading a scientific paper" reproduced on the last page of the exam. Use this
guide as a tool to summarize the introduction, material and methods, results, and discussion for two of the
three papers we
BME 4510 Final
30 April 2013
Problem 1: (0 Points). I am a senior and
plan to graduate this semester (Yes / No).
Problem 2 (65 Points)
1. Use what you have learned in this course to propose a reasonable strategy to generate a tissue-engineered
1. (5 Points) Write the rate laws for the following are elementary reactions assuming that the system is
closed (no in or out) and at constant volume.
2. (5 Points) One of the principle pathways
5 Feb 2014
Problem 1 (25 Points)
Fuchs and co-workers explored the possibility of using tissue-engineered skin as a method to deliver
proteins to the circulation. The general goal of the tissue-engineered skin would be as a drug del