Name: Ji Hea Lee
Date: April 23, 2012
Title: Dehydration of Alcohols to Generate Alkenes
I. Objective; To dehydrate unknown alcohols with a molecular formula C4H10O with
concentrated strong acids and analyze the products using gas chromatography to
Section: Thursday 10:30
Exercise # 1
Title: Melting Point Determination of Pure Compounds and Known Mixtures
Objective: The purpose of this experiment was to compare the melting points of pure substances
and mixtures of salicylic a
April 14, 2011
Section: Thursday 10:30
Title: Semimicro Fractional Distillation
Objective: The purpose of this experiment was to separate and analyze two liquid substances by
using distillation technique and utilizing the difference i
MCMP 205 Laboratory
Exercise 2. Electrophilic Aromatic Substitution: Nitration of Phenol
Required Reading: Chapter 16 in the lecture text. Pay special attention to sections 16.4 and 16.5.
Objective: This experiment has been designed to
Section 7.9 A,B,C, and E
1. Be able to analyze the stereochemistry of addition of known reactions. If you know any two of the following
list, the third can be deduced: (1) stereochemistry of the starting material; (2) stereochemistry
Supplement 6.2, Enantiomeric Excess
Continue from Wednesday, Feb. 20
1. What is meant by the terms enantiomeric excess (EE) and optical purity? How is EE related to the optical
rotation of a mixture of enantiomers?
Sections 6.66.7 (Skip Sec. 6.5)
Supplement 6.1, Chirality of Amino Acids and Proteins.
1. What does it mean to say that two molecules are diastereomers?
Diastereoisomers (diasteromers) stereoisomers that are not enantiomers; not mirro
Chapter 6 Introduction
Sections 6.16.4. There are plenty of animations to guide you through some of this material. See the Resources
section of the course web site. You will need a Shockwave Plug-in for your browser. Use Safari as your browser
Section 4.9B, Sections 14.414.5A. Read Sec. 14.5A through the top of p. 655, ending with the sentence in
italics corresponding aldehyde or ketone.
Then read Supplement 14.1 This supplement replaces the mechanistic discussion on p. 655 of your tex
Sections 4.8, 4.9 (Introduction and 4.9A)
1. What is the relationship between the rate of a reaction and its standard free energy of activation?
Rate the number of reactant molecules converted into product in a given time
Sections 6.9; Sec. 15.1C (p. 682)
Sec. 6.106.12 (Note that Sec. 6.11 is a review of the line-wedge and sawhorse notations that were covered in
Supplement 2.2; this will not be covered again.)
1. How is it that achiral molecules can ha
Continuation of Period 26
Chapter 13: Introduction; Sections 13.113.2; Section 13.3A,B,C
As with IR spectroscopy, we have animations that might help you with the theory of NMR. There are both
Windows and Macintosh versions. Do
Chapter 7 Introduction; Sections 7.17.5; Study Guide Link 7.2.
1. Explain why cyclic compounds with rings containing more than three carbons are not planar; explain why
cyclohexane is the most stable cyclic alkane containing eight or
Section 7.6. Skip the section on nomenclature, starting in the middle of p. 291 and ending with the problem at
the top of p. 292. Read everything else in this section.
For Problem 7.17because you are not responsible for the namesyou will need the
Continuation of the previous period
1. Understand the physical basis of the NMR imaging (MRI) experiment and how it is different from an NMR
experiment used for determining structure.
NMR tomography (magneti
Supplement 8.1, Section 3. Note that the Table of Solvents in your text (Table 8.2) is appended to Supplement
8.1 for convenience.
1. Understand the major solvent classifications.
Solute small amount
Solvent large amount
Supplement 9.1: Biological Leaving Groups in SN2 Reactions
2. Explain how substitution at the a- and b-carbons of an alkyl halide affects the rates of SN2 reactions.
Increased alkyl substitution at the car
Chapter 9 Introduction
Sections 9.1, 9.2|
Section 9.3A,B. (This is a reviewof material from CHEM 109 and will not be explicitly covered in class.)
1. Be able to identify a nucleophilic substitution reaction
Supplement 8.1 (continued) Sections 45
Supplement 26.1: Review of Enzyme Kinetics
1. Be able to describe the following phenomena and the important noncovalent interactions that lead to each:
MCMP 204 / Exam 3 / Fall 2010
EXAM WITH ANSWERS
Examination 3 with Answers
The questions marked with an asterisk (*) are from the discussion portion of the exam.
(18 points) Draw the major organic product in each of the following reactions. By-pro
Chapters 4, 14, and 15 Introduction; Sections 4.1-3; Sections 4.5 and 15.1.
1. What are alkenes and alkynes?
Alkenes hydrocarbons that contain one or more carboncarbon double bonds; sometimes called
olefins; simplest = ethylene; unsat
Medicinal Chemistry & Molecular Pharmacology (MCMP) 20400
COURSE SCHEDULE FOR SPRING SEMESTER 2014
All classes are in EE 129, 10:3011:20 AM
All laboratories are in RHPH 416
PLEASE NOTE CAREFULLY. Under Laboratory you will find the weeks experiment. This w
MCMP 204, Spring 2013
G. M. Loudon & L. L. Parker
Last name, first name_
Q UIZ 2
Instructions: Write your full name above (as it appears in university records; no nicknames please!). Before turning
your paper in, fold it lengthwise and put your name and s
1. Predict the order of bond lengths in a given molecule and the reasons for your choice.
Bond lengths increase significantly toward higher periods (rows) of the periodic table
Bond lengths decrease with incre
Sections 2.72.9 (Skip Section 2.6 for now.) Look at the functional group tables inside
the front cover. Chapter 26 Introduction and Section 26.1A,B. This is the first step in understanding
protein structure, which we will revisit at various point
Chapter 2 Introduction; Sections 2.12.3
Supplement 2.2: How to Draw Conformations
1. How are hydrocarbons classified?
Compounds that contain only the elements carbon and hydrogen
2. Why are there so many (estimate: 16 million and gro
Supplement 4.1: Electronegativity Effects of Hybridization. Hybridization Effects on Acidity and Basicity.
Section 4.4 (skip the discussion of boiling points; read the section on dipole moments).
1. How does an atoms h
Sections 2.42.5; SGL 2.1; FE 2.1
Supplement 2.1: Abbreviations of Substituent Groups
1. Apply the IUPAC system of nomenclature to branched alkanes and cycloalkanes.
1. The unbranched alkanes are named accord
Sections 1.51.9. It is expected that you will review the sections on atomic orbitals on
your own. The class will focus on molecular orbitals.
1. What is a molecular orbital (MO)?
Orbitals for the entire molecule
2. What aspec