Antimicrobial Drug Resistance
in Esc he ric hia c oli from Humans
and Food Animals, United States,
Daniel A. Tadesse, Shaohua Zhao, Emily Tong, Sherry Ayers, Aparna Singh,
Mary J. Bartholomew, and Patrick F. McDermott
We conducted a retrospective
Problem Set: Acid Base Equilibrium
1. Which is a stronger base, hydroxide or fluoride? Explain why.
Hydroxide is a stronger base because its conjugate acid is less acidic. The bases
conjugate acids are H2O and HF. Waters pKa is 15.7 and HFs pKa is 3.
Problem Set: Moles
1. The molecular formula of glucose is C6H12O6.
a. How many glucose molecules are in a 5.23 g sample of glucose?
5.23 g C6H12 O6 x
1 mol C6H12 O6
6.022 x 10 23 molecules
= 1.75 x 10 22 molecules of C6H12 O6
b. How many
-Medium broad peaks
at 3200 and 3500
indicating a primary
amine, and 1600
1500 peaks indicating a
-Sharp 1700 peak indicating a ketone
Problem Set: Resonance Structures
1. Draw the resonance structures that are generated from the following arrow
formalisms. Include lone pairs and formal charges.
Exploration - Acceleration due to Gravity Lab
Objective: Students will be able to use scientific inquiry to determine the acceleration
due to gravity of objects with varied masses in order to determine if mass has an effect on
the acceleration due to grav
1. Show how to make these molecules. You just need to show the carbon adding
steps each of these is reacted with H2/Pt after the carbon addition. Note: two of
these molecules cant be made!
2. Show the synthesis of the given molecules. To help gu
1. Name the following molecules
2. Assign stereochemistry to the following double bonds.
3. The reaction of HBr with an alkene is an electrophilic addition reaction. Explain
why it is given this name.
4. What is the regiochemistry of a reaction? W
For each structure below draw Newman projections down the C2-C3 axis for the most
and least stable conformations. Use the table below to calculate the torsional strain for
each of the conformations for the molecules. Which is the most and least strained?
For each structure below draw Newman projections down the C2-C3 axis for the most and least stable
conformations. Use the table below to calculate the torsional strain for each of the conformations for the
molecules. Which is the most and least strained?
CHEM242 NMR Workshop
Possible Compound Structures
Project 1 Day 2
OVERVIEW & RELEVANCE TO PROJECT 1:
In this lab session you will begin characterizing the organisms from your Winogradsky column
sample. In the coming weeks, you will be able to repeat the streaking and staining procedures
from this lab. Yo
Directions for the CHEM242 NMR assignment
Below are two documents:
CHEM242NMRSpectra(1) contains 26 13C and 1H NMR spectra,
labeled A through Z.
CHEM242NMRStructures(1) contains 26 chemical structures,
numbered 1 through 26.
The worksheet containing blank
CHEM 242 Organic Chemstry II Laboratory
Fall 2017 Laboratory Schedule (pages for the 7th Edition of the CHEM241 Text by Browne, Iverson, Anslyn and Foote)
*Please note that some experiments are multiweek experiments.*
Week Report Due
1. (like the extra credit) For (R)-3-chloro-4,4-dimethyl-1-hexyne. The two methyl groups are
diastereotopic. Draw the Newman projections down the C4-C3 bond. Draw all the staggered
Newman projections and rank them in order of stability. Using
Practice Problems Substitution and Elimination
1. Draw the products of the following reactions indicating stereochemistry where
appropriate. If there is no reaction, write NR.
2. Give the starting materials and/or reagents for the following reactions: