Experiment 11: Robinson Annulation of trans-Chalcone and Ethyl Acetoacetate
1. The product of this Robinson annulation has multiple stereoisomers.
a. How many different stereoisomers are possible?
b. Draw each of the stereoisomers, and
Chapter 3: Second Law of Thermodynamics
(Read: Atkins Chapter 3.1-3.4)
Recall First law of Thermodynamics: Conservation of energy (U, H)
But we dont know which process will actually occur and which do not
Chapter 9. Non-ideal Solutions (Read: Atkins 5.11-5.13)
9.1 Activities and Activity coefficients
Henry's law was one way of dealing with non-ideal solutions, but really only works for
very dilute solutions.
Chapter 4. Equilibrium (Read: Atkins 3.5, 3.7-3.9)
Weve heard about reaction equilibrium, phase equilibrium
What does it mean?
In a closed system, the amount of each substance remains constan
Chapter 7 One-component Phase Equilibrium (Read: Atkins chapter 4)
A phase is a homogenous portion of a system.
7.1 Phase Diagrams and the Phase Rule
Phase diagrams of 1-component system.
For a single material
Chapter 2: The First Law of Thermodynamics (Read: Atkins 2.1-2.6)
2.1 Two Important Concepts in Thermodynamics: Energy and Work
Work is done when an object is moved against an opposing force.
Experiment 1: Extraction
Chapters 9, 10 (sections 1-5, 7) and 11.
Chapter 10 (page 163): 1-5
Chapter 11 (page 173): 2
Why should the top layer be poured out of the top of the separatory funnel?
Why is it important to vent
Experiment 9: Synthesis of Benzocaine
1. Why do we use absolute ethanol in this reaction instead of the more common 95% ethanol?
2. Draw a mechanism for the acid-catalyzed reaction of p-aminobenzoic acid with ethanol.
3. The acid cataly
Experiment 8: Organozinc Chemistry
1. The reaction between allyl bromide and zinc is called an oxidative addition. Which reagent is
oxidized and which one is reduced?
2. The following reaction to make a Grignard reagent does not work. E
Experiment 3: Selectivity in the of Oxidation of 2-Ethyl-1,3-hexanediol
Chapter 10, section 6
Chapter 10 (page 163): 1, 3, 4
Chapter 11 (page 173): 2
Chapter 21 (pages 344 348): 1, 2, 5
Why should the top layer be poured out
Experiment 7: Chromatography of Spinach
Chapter 19, sections 1-4 and 7
Chapter 18 (page 269): 1-4
Chapter 12 (page 291): 1-5
Aquire 8-10 spinach leaves and tear into tiny pieces. Place in a mortar with 5 m
Experiment 2: Recrystallization and Melting Points
Chapter 15, Sections 1-5 and 8
Pre-Lab Questions: Chapter 14 (page 220): 1-2
Chapter 15 (page 235): 1-4, 7
What are three criteria you should consider when choosing a recrystallizat
Experiment 4: Combinatorial Synthesis of Azo Dyes
Why do we add sodium carbonate to the aminobenzenesulfonic acid in the first step of the
Why do we add sodium chloride to the dye solution before filtering it?