Proteins: Structure, Function, Folding
! Structure and properties of the peptide bond
! Structural hierarchy in proteins
! Structure and function of fibrous proteins
! Protein folding and denaturation
! Structure analysis of globular
Bio-Signaling - Lehninger Chapter 12!
12.1 General Features of Signal Transduction!
12.2 G ProteinCoupled Receptors and Second Messengers!
12.3 Receptor Tyrosine Kinases!
12.4 Receptor Guanylyl Cyclases, cGMP, and Protein Kinase G!
Membranes and Transport Lehninger Chapter 11!
! 11.1 The
! 11.2 Membrane
! 11.3 Solute
11.1 The Composition and
Architecture of Membranes!
! Membranes contain specia
6.1 What are Enzymes?
! Enzymes are catalytically active biological
6.1 An Introduction to Enzymes
! Specific, Efficient, Active in Aqueous Solution
! Most enzymes are globular proteins,
! Catalysts, Proteins, Reaction Typ
Foundations of Biochemistry
the Chemistry of Living Matter
! Distinguishing features of living organisms
! Structure and function of cells and organelles
! Roles of small and large biomolecules
Water and Aqueous Solutions
! Types of non-covalent interactions between molecules
! Properties of water THE medium for life
! Hydrophobic - nonpolar - moieties aggregate in water
! Solute effects on bulk properties of water
Amino Acids, Peptides,
Structure and naming of amino acids
Structure and properties of peptides
Ionization behavior of amino acids and peptides
Purification and assay methods
Peptide sequencing and chemical synthesis
Protein sequence an
Nucleotides and Nucleic Acids Lehninger Chapter8!
8.1 Basics !
8.2 Structure !
8.3 Chemistry !
8.4 Nucleotide Function !
Canonical and Minor Bases!
Naming and Drawing!
Base Stacking and Pairing!