Actin-Myosin Cross Bridge Cycle
1. Intracellular levels of calcium ions increase; calcium attaches to C subunit of troponin. 2. Troponin changes shape and pulls tropomyosin off of actin binding site. 3. Myosin head binds to actin 4. Inorganic phosphate is released into the sarcoplasm 5. Power stroke moves actin past myosin and shortens sarcomere 6. ADP released into sarcoplasm 7. ATP reattaches to myosin causing the actin-myosin complex to dissociate 8. If calcium present, rebinds troponin and the cycle goes again 9. If calcium is absent, troponin will cover the binding sites of actin and physically block cross-bridge formation
Functions of the Cardiovascular System
1. Transport oxygen and carbon dioxide 2. Transport metabolic wastes 3. Distribute nutrients 4. Distribute hormones 5. Regulate body temperature 6. Protect the body from blood loss and disease
This class was tough.
While this course was challenging, it was a great course for anyone interested in the medical field or any field of study involving the human body. Dr. Pearcy ensures that his students don't just kind of know the material, he makes sure that you REALLY know the material. The lab material helped to supplement the lecture material. Additionally, you are required to read a book for lab and take chapter quizzes each week to expand not only your knowledge of physiology but to expand you literature background as well. In class quizzes and tests require thinking through the problems and critical thinking, but are very manageable if you put in the effort and time. Overall, the course is challenging but very rewarding and educational.
Not only did Dr. Pearcy cover the basics, he also delved into the depths of human physiology and how it can apply to real life situations. I learned not only the material covered in this class, but I also learned how to effectively study and how to push myself to be the best student I could be while taking this class. Also, this course prepares you for further physiology courses that you may take in the future.
Hours per week:
Advice for students:
Be involved in class discussions, for id you're not Dr. Pearcy will call on you to force you to be involved. Don't be afraid to ask questions in class or outside of class. Dr. Pearcy is a friendly person and is willing to help clarify information. While studying for quizzes and tests, be prepared for short answer questions to go into great detail. Always know what happens and why it happens. Also, be sure to have a firm grasp on the concepts, for his multiple choice questions on the tests require critical thinking and analysis of the material. He offers extra credit on every test, it usually covers current events such as the election, world series, super bowl, capitals of countries, etc. I would just say to study until you know what is going on, and then study more. Don;t be afraid to utilize the peer tutors on campus and Dr. Pearcy's office hours as well. Memorization isn't enough to succeed in this class, complete understanding is the goal.