Molecular bases of cancer
When cancer appears, we generally classify it based on traditional pathologic prognostic and
predictive factors (for example in breast cancer), such as:
Tumour, node, metastases classification (TNM).
Lymph node status.
METASTASIS Appearance of neoplasms in parts of the body remote from the site of the
Seed and soil theory: semilla y suelo. Cancerous cells travel through the circulation until it finds
a soil (tissue) where it can live.
Stephen Paget scruti
Bioinformatics its a good way to globalize the information and at the same time it is a way of
access for the patient to the medical information (connect with patient).
Different levels of relevant information
Electronic patient course
Introduction What is biotechnology?
Biotechnology = bios (life) + logos (study of or essence) Litera'lly the study of tools
from living things.
Classic Any technique that uses living organisms to make a product or run a process,
Transformation by microinjection.
Another technique is to infect stem cells with foreign DNA. Then, we inject those cells
into a blastocyst. The handicap is that this blastocyst has its own cells, so the offspring
will have two kinds of cells (with differ
We can increase the size of fish with modifications to their genome and also adding
particular proteins (as GH) se pueden resolver problemas de malnutricin. Once
inserted in the fishs DNA the protein is expressed in:
- Cold waters reduces the
UNDERSTANDING MOLECULAR DIAGNOSIS AND
BIOMARKERS IN HUMAN DISEASE. CM 14.
Biomarkers help in diagnostic pathology. Now we try to focalize on the patient, to
cure with specific and individual treatments. A new type of medicine which helps
to cure patient i
From the laboratory
The three mayor health problems of the prostate gland in adults
Prostatitis: inflammation. It can be related with bad sexual behaviour.
Benign Hyperplasia (BHP): prostate is bigger, but it is not related with cancer.
Food and Plant biotechnology
Food biotechnology employs the tools of modern genetics to enhance beneficial traits of plants,
for food production. It involves adding or extracting selected genes to achieve desired traits. For
example, thanks to biotechnolo
Prognosis can be derived from the gene expression of the primary tumour. The
prognostic gene profile provides a powerful tool to tailor adjuvant systemic treatment.
a) Metastatic potential is an early and inherent ability rather than late and