Antigen Capture and Presentation to Lymphocytes
Adaptive immune responses are initiated when the antigen receptors of lymphocytes
The antigen receptors of B lymphocytes namely, membrane-bound antibodies can
recognize a wide variety of
Study Guide for General Immunological Concepts Exam
This is a general guide. I recommend answering the questions at the end of the chapters as an
assessment of your knowledge.
1. Know the terms/vocabulary which were defined in the book (bold
Introduction to the Immune System
Immunity - resistance to disease, specifically infectious disease
Immune System the collection of cells, tissues, and molecules that mediate resistance to
Immune Response coordinated reaction of the immune syst
Innate Immunity Notes
Innate Immunity protection against infections that relies on mechanisms that exist before
infection, are capable of rapid responses to microbes, and react in essentially the same way to
The innate immune system inc
1. What types of antigens may induce immune responses that cause hypersensitivity reactions?
Hypersensitivity reactions may arise from uncontrolled or abnormal responses to
foreign antigens or autoimmune responses against self anti
Humoral Immune Responses Review Questions
1. What are the signals that induce B cell responses to protein antigens and polysaccharide
Humoral immune responses to a protein antigen are initiated by binding of the protein
to specific Ig receptors
Effector Mechanisms of Humoral Immunity
1. What regions of antibody molecules are involved in the functions of antibodies?
The antigen-binding (Fab) regions are used to bind to and block the harmful effects of
microbes and toxins. In other words the Fab
1. What is immunological tolerance? Why is it important?
Immunological tolerance is the unresponsiveness to self antigens. It is a lack of
response to antigens that is induced by exposure of lymphocytes to these antigens.
Antigen Recognition in the Adaptive Immune System
Specific antigen recognition is the task of two structurally similar types of cell surface
receptors of lymphocytes: membrane-bound antibodies on B cells and T cell receptors
(TCRs) on T lymphocytes.
Tumors, Transplants and the Immune System
1. What are the types of tumor antigens that the immune system reacts against? What is the
evidence that tumor rejection is an immunologic phenomenon?
Tumor antigens that are recognized by tumor-specific CD8+ T c