1) First Biological Psychiatry
a. Primarily about eugenics and Neuroanatomy
1. Know at a min. what it is
2. Who invented it
3. Diferent ways of doing eugenics
4. Diference btw positive and negative eugenics
ii. What does the AUTHOR of your boo
Who he was. Book he wrote.
American psychiatrist who specializes in the area of depression.
oHe considers depression to be a serious illness with tangible
oCriticizes society for romanticizing depression.
(Know graph on transmitters)
Know monoamines, serotonin, and catecholamines
Xanax is a classic antianxiety drug (benzodiazepine). First line of treatment
for anxiety would be:
oDont call the
What does neuroleptic mean?
Neuroleptics = antipsychotics
oTerm used for drugs that diminish psychosis (coined by Delay
oTranquilizing psychiatric medication primarily used to manage
psychosis, as well as disordered thought (schizo and bipola
MAD MED MIDTERM
Otto Loewi, professor of pharmacology, discovered rst neurotransmitter.
Acetylcholine mediates transition of the nerve impulse from one nerve to
the next. Twin studies (e.g. Danish by Kety) showed that there was a
biological basis in schiz
Risperidal, and Childhood Bipolar Disorder
Until recently, ADHD treated with stimulants in 1990s, Biedelman
said kids don't have ADHD, they have bipolar disorder diagnosis
increased ten thousand fold.
Massive shift seen away from SSRIs an
Iproniazid discovered by Nathan Kline- First monoamine oxidase
inhibitor. First antidepressant ever marketed- originally used for
treatment of TB- doctors noticed it made patients euphoric. First widely
used, later withdrawn-
Exam 1 Review
psychiatry- evolved from idea that hospitalization could be therapeutic.
Before 1700s there were institutions for mentally ill, primarily custodial. Warehouses where people were kept
under very bad conditions, roof over heads, keep away from
What drug when it was introduced was thought to produce a chemical
Chlorpromazine in book (CPZ = thorazine)
How does reserpine work?
Mechanism of action
oCompletely depletes all monoamines in the body by preventing
storage of NT in ves
Introduction of Stimulants to Treat ADHD
Know this history
Started in the 1930s by Bradley
1930s Alles discovers CNS stimulant effect of amphetamine
1937 Bradley uses amphetamine (Benzadrine) to treat childhood
Late 1950s Ritalin (Methy