Introduction to RNA Structure
Unique Aspects of RNA Structure: 2. C2 OH group (alkaline hydrolysis). 3. Sugar Pucker C3-endo. 4. Helix is A-form. 5. There are unusual H-bonding pairs for example, non-Watson-Crick pairs, base triplets.
Polynucleotides in a helical arrangement display order which can be described in terms of helical parameters. Strand orientation parallel or antiparallel Helix configuration right-handed or left-handed Base spacing or stacking in
Polynucleotide Structure - Its important to keep in mind that the Function of a molecule is a direct consequence of Structure and Chemistry. Its important to keep in mind that these molecules are: 1. Three-dimensional 2. Dynamic and Flexible
N2 Fixation Pentose Phosphate Pathway Glutamate / Glutamine Ribose Nucleotide Biosynthesis Amino Acid Biosynthesis Citric Acid Cycle and Others
Nucleotides can be synthesized by de novo or salvage
Course materials: http:/courses.ncsu.edu/bch453/lec/001/
Introduction The Four Classes of Biological Macromolecules: Nucleic Acids Pr