Review of histamine
Histamine is a small molecule produced in specialized cells throughout the body. The
compound plays an important role in allergic reactions and the regulation of gastric acid
In the vascular system, histamine dilates small b
1. Cardiac disease: how and when to determine classifications, activity modifications for
each class, medical management, antepartum, intrapartum, and postpartum nursing
management, assessment of cardiac decompensation.
Cardiac changes during p
Key Points: Angina
Angina pectoris is defined as sudden pain beneath the sternum, often radiating to the left
shoulder, left arm, and jaw.
Anginal pain occurs when the cardiac oxygen supply is insufficient to meet oxygen
Just the Facts: von Willebrand Disease
Hereditary bleeding disorder characterized by prolonged bleeding time, moderate
deficiency of clotting factor VIII and impaired platelet function from a deficit of von Ville
brand factor (vWF)
Interpreting Labs: Iron related labs
Measure the amount of iron bound to transferrin in blood plasma.
Total Iron-Binding Capacity (TIBC):
TIBC measures the amount of iron that would appear in plasma if all the transferrin
For routine therapy, heart failure is treated with three types of drugs: (1) diuretics,
(2) agents that inhibit the RAAS, and (3) beta blockers. Other agents (e.g.,
digoxin, dopamine, hydralazine, nesiritide) may be used as well
Drug Therapy for Hypertension
Arterial pressure is the product of cardiac output and peripheral resistance. An increase in
either increases the BP.
Cardiac output is influenced by four factors: (1) heart rate, (2) myocardial contractility
(force of contra