Brittney Lab 3: Synthesis of Aspirin
Empty flask 88.0g
2 small crystals left after liquid poured out.
Crystals and flask = 91.889g
TT1: Ester: yellow color
TT 2: Phenol: purplish color
TT 3: Phenol reaction: yello
Quiz 3, Radical Halogenation, Chem 341
1. Write the mechanism (propagation steps only!) for the reaction of propane with bromine to give 2bromopropane. Include detailed arrow-pushing.
2. Rank the stability of the following radicals, from 1 (mos
1. For the compound methylamine, CH3NH2, which of the following statements is true for the nitrogen atom?
It has a formal +1 charge.
It has a formal -1 charge.
It has no formal charge, but has a slight nega
Quiz 4, Stereochemistry, Chem 341
1. For each structure, a) star any chiral carbons, b) label each chiral carbon as (R) or (S) and c)
indicate any molecules that are chiral. [Two tools for assigning chirality: chiral carbons and
planes of symmetry
1. Which of the following statements regarding compounds A-C is true?
a. B has the highest boiling point and the lowest water solubility
b. A is highest boiling; B has the lowest water solubility
c. C is highest boili
Organic Synthesis Strategy
The preparation of more complex molecules from
commercially available starting materials via a multistep sequence of transformations.
O O OH HO PhOCO H AcO O
Quiz 06 December 04, 2006
3 Points Each. Please mark your answers on the scantron sheet. You may keep this copy. 1. How many different resonances would the following molecule show in the 1H NMR spectrum?
CH3 O CH3 C CH3 C O CH2 CH2 CH3
Quiz 05 KEY November 29, 2006
3 Points Each. Please mark your answers on the scantron sheet. You may keep this copy. 1. Molecules absorb infrared radiation at frequencies that relate to . . . ? (a) the number of hydrogens in the molecule (b) the rate of c
Quiz 02 October 05, 2006
3 Points Each. Please mark your answers on the scantron sheet. You may keep this copy. 1. Which of the following substituents would have the lowest Cahn-Ingold-Prelog priority
Chem 342 Jasperse Test; 2 Version 1 Name'
t. Predict the HNMR spectrum. Include the approximate chemical Shifts (its, 2s, etc), the
integration, and the splitting (can use 3' for singlet; d for doublet; t for triplet q for quintet;
and m for multi
Chem 360 Jasperse
Ch. 18b Aldehydes and Ketones. Reactions, Mechanisms
Note: Anything inside of brackets [ ] represents something that isnt or cant be isolated. Often
something in brackets is an intermediate on the way to something
Instructions: You will need four raw eggs (more in case of mistakes), vanilla extract, and
vinegar to complete this activity! Copy this worksheet into a new document, and type all
responses into your new document. Place
Sickle Cell Anemia
Instructions: Copy this worksheet into a new document, and type all responses into your new
document. Click on the web links listed below, and answer all prompts in complete, well
developed sentences. Place your com
Brittney Lab 2: Chemistry Demo
Experiment 1: Perform a Decomposition Reaction
1. What was the change in mass of the contents in the crucible? Compare the mass after
heating to the mass before heating.
2. The color change of
Qgiz 3, Radical Halogenation, Chem 341 Name: ll; Nib: UL lifJIli-ff7l
Due: _. m
05., Hz;- Ll; Fl-
]. Write the mechanism (propagation steps only!) for the reaction of propane with bromine to give 2-
bromopropane. Include detailed arrow-pushing.
e a 6:9
Chem 341 Jasperse Quiz #1 Due: DE R, . 10 Name: M! (h C f/RO chS O n
1. For the compound methylamine. CHsNI-lz. which of the following statements is true for the nitrogen atom?
a. it has a formal +1 charge.
b. It has a formal 1 charge-
@It has no formal c
Organic Chemistry -I - J asperse Name miCl mi a RUE/Cs Uri
Testl U: .ir; n
Intro and Review
Structure and Properties of Organic Molecules
Structure, Nomenclature, and Conformation/Stereochemistry of Alkanes
1. Draw the correct Lewis HUME o CH3CH2CHCHCOZCH
-. - h J .- r.
Chem 34l-Jasperse Name: W; l (1,311? Hf. EU J13, l E: i~ y 1
Test #4 Conjugation, Diels-Alder, Aromaticity, Aromatic Reactions
1. Provide either the Name or Structure for the Following Chemicals (6 points).
a. ochlorotoluene b. U
Organic Chemistry 1 - Jaspcrse
The Study of Chemical Reactions
Alkyl Halides and their Reactions: Nucleophilic Substitution and Elimination
1. Predict the major organic product for each of the following. (1 major structure is all t
Quiz 01 - KEY September 13, 2006
3 Points Each. Please mark your answers on the scantron sheet. You may keep this copy. 1. What is the hybridization of the carbon indicated below?
a) not hybridized
2. Which of the following compounds
2006 Nobel Prize in Chemistry
"for his studies of the molecular basis of eukaryotic transcription"
Prof. Roger Kornberg Dept. of Structural Biology Stanford University School of Medicine
Heterocycles in DNA and RNA
NH2 N N H N N N N H N NH2
Nuclear Magnetic Resonance
A spinning charged particle generates a magnetic field. A nucleus with a spin angular momentum will generate a magnetic moment ().
If these tiny magnets are placed in an applied magnetic field (B
Axial and Equatorial Positions of Cyclohexane
Pink - Axial Blue - Equatorial
Cyclohexane Axial Positions More Crowded
1,3-diaxial interaction axial methyl H CH3 ring flip H H H H
equatorial methyl H H H H H CH3
1.8 kcal/mol more stable con
anti Butane Conformations
Butane Conformations H3C H C H HH C CH3
view down this axis to see Newman Projection
H anti-methyls - 180 H
CH3 Newman Projection anti-staggered
eclipsed Butane Conformations
Butane Conformations H H CH3 Newman
Answers to Additional Problems Chapter 10-11
Additional Practice Problems 1. Which of the following diastereomers would undergo E2 elimination faster. Explain.
Br Br most stable conformation cannot eliminate H H
must be in this conformation with H's
Suggested Problems Chapter 06
Problems from your text 6.3, 6.4, 6.5, 6.7, 6.10, 6.11, 6.14, 6.16, 6.18, 6.19, 6.24, 6.26, 6.29, 6.35, 6.39, 6.41, 6.42, 6.44, 6.49, 6.53
Additional Practice Problems 1. a) In the following reaction of the addition of HCl to
Answers to Additional Problems Chapter 2
Additional Practice Problems Briefly explain why protonated triphenylmethanol would more easily dissociate into the corresponding cation and water than protonated tert-butanol.
CH3 H3C C O CH3
CH 3 H 3C C CH 3