BCH311 Tutorial 6
Thursday, February 27, 2014
Properties of DNA Replication (From Last lecture)
5 to 3 direction only
theta structure -> double in H-Thymidine
(saw two replication forks however this
Cairns, Hubermang, Rigggs?
was not enough
BCH311 Tutorial 5
Thursday, February 13, 2014
Properties of DNA Replication
He interpreted: some of the properties of DNA replication.
Kornberg, et al: Initial Characterization of DNA polymerase
DNA synthesis 5 to 3direction only When new n
DNA Replication is a Common Drug Target
A number of therapeutic drugs used to treat cancers and viral infections act by inhibiting
DNA replication. The goal of this task is to familiarize you with how one of these drugs
work. Drugs that target DNA replica
Discovery of DNA Polymerase
by I. R. Lehman
This review is a personal account by one of the discoverers of DNA polymerase I. It is a
nice illustration of how teamwork and incremental advances can occasionally lead to
1. what would be the effect on protein's function and structure if all possible
were made at
the first position of
a lysine codon in a gene encoding a particular protein?
Lysine = AAA, AAG * POSITIVE CHARGE
BCH311 Tutorial 2
Thursday, January 23th 2014
1) Which of the following types of RNA carries the
instructions for making proteins?
d) all of the abov
BCH311 Tutorial 1
Thursday, January 16th 2014
My Contact Information
BLACK BOARD is the BEST way to ask questions.
What is DNA?
BCH 311 Tutorial 12
E. Coli, have rare codons
not all tRNAs are expressed equally. you have 64 codons, not all are expressed
61 different codons that code for amino acids. RIPL have codons that are expressed in really low concentration in E. Coli cells
1) Propose the most stable triple base pairing arrangement that could
result for the following three bases: A, U, C.
2) Explain how either a) Southern Blotting or b) FISH could be used to
detect the BCR-ABL gene fusion associated with chr