Biochemistry - Problem set 1
August 22, 2016
Problem Set 1: Solution Key
1. (5 points, 5 min) Rank, from highest to lowest, the hydrogen bond strength of the following groups; assume the H-bond
acceptor is the carbonyl (C=O) group. a) -N-H b) -O-H c) S-H
Biochemistry - Problem set 2 August 29, 2016
Problem Set 2: Due Sunday September 4 Total Time required: ~ 85 min
1. (4 pts, 10 min) A Venn diagram that organizes the amino acids
by the properties of their side chains is shown on the right.
Glycine is omit
Biochemistry I
Problem Set 5
February 14, 2016
Y - Fractonal Saturaton
Due Monday February 22, 2016
~90 minutes.
1. (21 points, 20 min) The Jmol page for this question contains structures for the complex between two
NH3+
different Fv fragments (A & B) bou
Biochemistry - Problem set 1
August 21, 2016
Problem Set 1: Due Sunday Aug 28 by 5:30 PM Total time required ~45 min.
Calculate use a formula to give quantitative answers.
Sketch - you need not calculate the curve, just try to reproduce its general featur
Biochemistry Spring 2015
Exam III
Name:_
Instructions. This exam consists of 100 points on 6 pages. Allot 1 min/2 points. On questions with choices, all of
your answers will be graded and you will be given the best grade for that question.
Page
1
1. (4 pt
03-232 S2016
Exam II
Name:_
Instructions: this exam consists of 11 questions on 5 pages, for a total of 100 points. On questions with choices,
all of your attempts will be graded and you will be awarded the highest grade. Please use the space provided
or
03-232 Biochemistry
Exam III 2016
Name:_
Instructions: this exam consists of 14 questions on 6 pages, for a total of 100 points. On questions with
choices, all of your attempts will be graded and you will be awarded the highest grade.
1. (4 pts) X-ray Dif
03-232 Spring 2014
Exam II
Name:_
Instructions: This exam has 6 pages and 13 questions and is out of 100 points; you should allot 1 min/2
pts. Please use the space provided or the back of the previous page. On questions with more than one
choice, all of y
03-232 Biochemistry
Exam III - S2014
Name:_
Instructions: This exam consists of 100 points on 6 pages. Please use the space provided to answer the question,
or the back of the preceding page. In questions with choices, unless otherwise indicated all your
03-232 Spring 2015
Exam 2
Name:_
Instructions: This exam consists of 100 pts, 14 questions, 6 pages. On questions with choices all of your attempts
will be graded and you will receive the best grade. Allot 1 min/2 points.
Drug I
1. (18 pts) HIV reverse tr
03-232
Exam 1 S2016
Name:_
Instructions: this exam consists of 14 questions on 5 pages, for a total of 100 points. On questions with choices,
all of your attempts will be graded and you will be awarded the highest grade. Please use the space provided or
t
03-232 Biochemistry Exam I Spring 2014
Name:_
This exam consists of 6 pages and 11 questions with 1 bonus question. Total points are 100. Allot 1 min/2
points. On questions with choices, all of your answers will be graded and the best scoring answer will
Dina Nayel
Biochemistry I
Problem Set 3
Due Tuesday September 20, 2016
September 6, 2016
This problem set should take you ~90 min to complete.
1. (6 pts, 15 min) You are growing a 0.5 L culture of bacteria in growth media that is buffered with 0.05 M
phos
Dina Nayel
Biochemistry I
Problem Set 4
September 25, 2016
Due Sunday October 2, 2016
Total time required: ~ 120 min.
1. (26 pts, 25 min). The following 37 residue peptide can adopt a stable fold in solution.
Ser-Ala-Cys-Val-Asp-Val-Asn-Pro-Gly-Ser-Ser-Ly
Biochemistry - Problem set 2
August 31, 2016
Problem Set 2 - Key
1. (4 pts, 10 min) A Venn diagram that organizes the amino acids by the
properties of their sidechains is shown on the right. Glycine is Charged
Pro
Leu
Lys
Non-polar
omitted since its sidec
Free Energy of hydrolysis (kJ/mol):
phosphoenolypyruvate -61.9
-30.0
ATPADP
Glucose-1-P
-20.9
Glucose-6-P
-12.5
Biochemistry I: Formulas and Constants
Enzyme Kinetics:
For [E]+[S] [ES] [E]+[P]
Vmax= kCAT [ET]
KM = (kOFF+kCAT)/kON
v=
VMAX [ S ]
K M + [S ]
Dina Nayel
03-232 Biochemistry Fall 2016
Problem Set 8
Due Sunday Nov 6, 2016
Time required ~ 75 min.
1. (10 pts, 20 min) Two experiments were performed to
determine the quaternary structure of HIV reverse transcriptase
as well as the molecular size of ea
Dina Nayel
Biochemistry
Problem Set 6
Due Sunday October 16, 2016
October 10, 2016
Estimated time: ~ 100 min
KM = 0.1 mM
kcat = 1000 sec-1
1. (8 pts, 10 min) You work for a pharmaceutical Mushroom
Yeast
K
=
0.01
mM
kcat = 100 sec-1
M
company that produces
Dina Nayel
Biochemistry I
Problem Set 5
October 3, 2016
gtyuioDue Sunday October 9, 2016
~ 90 min
1. (5 pts, 15 min) What is the relationship between the microscopic and macroscopic association constants for
a trimer?
2. (12 pts, 20 min) This problem inve
03-232
Exam 1 S2016
Name:_
Instructions: this exam consists of 14 questions on 5 pages, for a total of 100 points. On questions with choices,
all of your attempts will be graded and you will be awarded the highest grade. Please use the space provided or
t
03-232 S2015
Exam 1
Name:_
Instructions: This exam consists of 100 pts, 14 questions, 5 pages. On questions with choices all of your attempts
will be graded and you will receive the best grade. Allot 1 min/2 points.
1. (6 pts) The following shows two drug
03-232 S2015
Exam 1
Name:_
Instructions: This exam consists of 100 pts, 14 questions, 5 pages. On questions with choices all of your attempts
will be graded and you will receive the best grade. Allot 1 min/2 points.
1. (6 pts) The following shows two drug
Biochemistry
Coverage
: Lectures 1-11 (Ligand Binding).
Study Hints:
1. Understand the solution to problem sets 1-4,
in-class examples, and recitation sessions.
2. Read the lecture notes first, then the relevant
sections of the text if things are unclear.