CSCI2820: Expectation-Maximization Haplotype Phasing
October 23, 2013
Informally, expectation-maximization can be described in 4 steps:
1. Initialize haplotype frequencies. The most common initializat
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CSCI2820: Medical Bioinformatics Homework 3 Solution
Problem Research Question Linkage Disequilibrium vs. Informativeness (35%)
We present here a sample of answers supplemented with key insights fro
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CSCI2820: Medical Bioinformatics Homework 2 Solution
Problem Tag SNPs in Dierent Populations (Required - 20%)
Analyze the dierences between the sets of tagging SNPs selected for each population.
Why
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CSCI2820: Medical Bioinformatics Homework 1
Due: 11:59PM October 1, 2013
This homework involves the use of Mathematica. You can either pass in the Mathematica notebook with the questions answered or
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CSCI2820: Medical Bioinformatics Homework 1 Solution
Problem 1: A Bit of Mathematica Programming
1. Program the equation to compute r2 .
rsquared = (probs[1] - pi1plus*piplus1)^2 / (pi1plus*pi2plus*
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CSCI2820: Medical Bioinformatics Homework 2
Due: 11:59PM October 22, 2013
Please complete all problems marked required; also, complete one of the following
problems: Problem Expectation Maximization
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CSCI2820: Medical Bioinformatics Midterm
Due: 11:59PM November 14, 2013
Choose to complete either Problem 2 (BIO) or Problem 3 (COMP) problem but not both. The
other questions are required. Please h
Medical Bioinformatics (CSCI295-L)
Genome-Wide Association Studies, Protein Folding and
Immunogenomics
Sorin Istrail
November 2010
SYLLABUS
Contents
1 Short Introductions
2
2 The Hardy-Weinberg Model
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CSCI2820: Medical Bioinformatics Homework 4
Problems 1-2 are due on November 27, 2013.
Problem 3 is due on December 4, 2013.
Please handin your submission of Problems 1 and 2 by emailing it to Derek
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CSCI2820: Medical Bioinformatics Homework 4 Solution
Problem 1: Minichiello-Durbin Algorithm and Ancestral Recombination Graph Reconstruction
Three individuals, changing objectives (20%)
Because the
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CSCI2820: Medical Bioinformatics Homework 3
Due: 11:59PM November 5, 2013
Handin your submission by emailing it to Derek [email protected] with subject
csci2820 hw3 handin or in class if hand-written