1. Explain the mechanism associated with the development of adverse skeletal changes from excess
Excess glucocorticoids inhibit replenishment of osteoblasts, and promote osteocyte apoptosis. Also they inhibit
calcium absorption, and accel
FIV A Normal rhythm _1 sec F Atrial utter with 1:1 AV conduction
G Monomorphic ventricular tachycardia
B Premature ventricular beat WW/X/VWWW/
therapyupdate Acute heart failure syndromes
Pharmacotherapy for acute heart failure syndromes
James C. Coons, Molly McGraw, and Srinivas Murali
t least 5 million people in the
United States have heart failure
(HF) and another 550,000 are
new england journal
mechanisms of disease
Antiinflammatory Action of Glucocorticoids
New Mechanisms for Old Drugs
Turk Rhen, Ph.D., and John A. Cidlowski, Ph.D.
nflammation is a reflexive response to infection, the bindin
n e w e ng l a n d j o u r na l
m e dic i n e
Glucocorticoid-Induced Bone Disease
Robert S. Weinstein, M.D.
This Journal feature begins with a case vignette highlighting a common clinical problem.
Evidence supporting various strat
Local and General
Depress the CNS to produce loss of
consciousness, loss of responsiveness to sensory
stimuli, including pain and relaxation of muscles
They are either volatile liquids or gases
vaporized in oxygen
DRUGS USED TO TREAT
Read- Chapter 37 Pharmacotherapy of
Understand the mechanism of action,
clinical usefulness of the classification
system for antiarrhythmic drugs
Profile on Diabetes &
Insulin is secreted from -cells of the islets of
Langerhans of the pancreas.
Insulin secretion is stimulated by high plasma
glucose levels and is inhibited by low plasma
Pain management with
What is pain?
The sensation of pain is comprised
of at least two elements:
1. Local irritation- stimulation of
2. Recognition- of the pain within the
Cardiovascular Pharmacology 3
B) Read- Chapter 38 Pharmacotherapy of Coagulation
C) Dyslipidemic Drugs
D) Read- Chapter 29 Pharmacotherapy of Hyperlipidemia
Drugs used in coagulation disorders
Platelet aggregation and thrombus
Question 1 of 10
Drugs that are highly bound to plasma albumin will have a larger volume of distribution
Question 2 of 10
Drugs must have a certain degree of water solubility to get through the BBB
Question 3 o
STUDY QUESTIONS FOR CONGESTIVE HEART FAILURE
1. Recall as many similarities and differences as you can between systolic and diastolic heart
Similarities: The problem is located in the left ventricle.
Differences: In systolic failure the ventric
Question 1 of 15
Question 5 of 15
Systemic corticosteroids improve blood glucose levels in
Based upon the mechanism of glucocorticoid agents
they may useful for all of the following except:
A. Suppression of allerg
Question 1 of 20
General principles of anti-infective therapy are:
A. Clinical judgment of microbiological factors
B. Definitive identification of a bacterial infection
and the microorganisms susceptibility
C. Optimal route of administration, d
1. In your own words, characterize heparin-induced
Heparin-induced thrombocytopenia (HIT) develops as a result of an
abnormal response to heparin therapy. HIT is characterized by a decrease in
the platelet count and an increase in
Briefly answer the following questions.
References are NOT required.
1.Name the enzyme that breaks down acetylcholine in the synaptic cleft.
2.What is the neurotransmitter at the neuromuscular junction?