Chapter 14 RNA molecules and RNA processing
14.1 Many Genes Have Complex Structures
For the most part genes and proteins are colinear: direct correspondence bw the ntd sequence of
DNA and the amino acid sequence of proteins
Genetics Exam 2
Below is a cross between two haploid yeast strains.
ura3, TRP1 X URA3, trp1
The cross produces asci of the following type:
Part 1 Introduction:
Describe the genotypes given (use your notes). The first two are already done.
DD homozygous, dominant
D. ss _
E. Yy _
F. WW _
In humans, brown eye color (B), is dominant over bl
Prof: Janice Fischer
EXAM #1 (Learning Objectives in Classes 1-3)
January 28, 2014
No questions will be answered during the exam. Figuring out what the questions mean
is part of the exam.
Read the questions carefully
The ABO Blood Group is the most popular of the many others that are
known. At one time, forensic blood samples were used to distinguish
between individuals using the ABO system.
However, this did not work. Why?
The ABO system is a system that mea
Name: _ Period: _ Date: _
Genetics practice test
Identify the choice that best completes the statement or answers the question. Indicate your answer choice with
an UPPER CASE letter in the space provided.
1. Usually, an egg cell fr
LECTURE 20 EUKARYOTIC GENES AND GENOMES II In the last lecture we considered the structure of genes in eukaryotic organisms and went on to figure out a way to identify S. cerevisiae genes that are transcriptionally regulated in response to a change in env
Lecture 23 Transgenes and Gene Targeting in Mice I
In the next two lectures I will be telling you about some of the ways in which we can study gene function in higher eukaryotes, more specifically in the laboratory mouse Mus Musculus. I will be doing this
Lecture 19 EUKARYOTIC GENES AND GENOMES I For the last several lectures we have been looking at how one can manipulate prokaryotic genomes and how prokaryotic genes are regulated. In the next several lectures we will be considering eukaryotic genes and ge
Lecture 21 Eukaryotic Genes and Genomes III Cis-acting sequences In the last lecture we considered a classic case of how genetic analysis could be used to dissect a regulatory mechanism. This analysis was contingent upon having "clean" phenotypes associat
Lecture 26 In this lecture we will consider how allele frequencies can change under the influence of mutation and selection. The first consider the conversion of a wild type gene to an altered allele by mutation: A a =mutation rate (probability of a mutat
Lecture 25 Population Genetics Until now, we have been carrying out genetic analysis of individuals, for the next three lectures we will consider genetics from the point of view of groups of individuals, or populations. We will treat this subject entirely
Lecture 27 Effects of Inbreeding: Today we will examine how inbreeding between close relatives (also known as consanguineous matings) influences the appearance of autosomal recessive traits. Note that inbreeding will not make a difference for dominant tra
Lecture 24 Transgenes and Gene Targeting in Mice II
In the last lecture we discussed sickle cell disease (SCD) in humans, and I told you the first part of a rather long, but interesting, story describing how a mouse model for this human disease has been g
Lecture 18 18
In the preceding examples of bacterial gene regulation, we have used known regulatory mechanisms to see how mutations in different elements of the system would behave in dominance tests and cis/trans tests. However, one is often trying to l
Genetics Lecture 1 We will begin this course with the question: What is a gene? This question will take us four lectures to answer because there are actually several different definitions that are appropriate in different contexts. We will start with a ph
Plasma is a mixture of water, sugar, fat, protein, and potassium
and calcium salts. It also contains many chemicals that help form
blood clots necessary to stop bleeding. More than 92% of plasma is
water. Which is
There are only 106 kinds
of stuff in the world.
Each type of stuff is called
that are composed
of only one type of
Living things are made up of
Lecture 4 4
From the last lecture, we followed gene segregation in a cross of a true breeding shibire fly with a wild type fly.
Shibire x wild type
F1: all not paralyzed
F2: 3 not paralyzed : 1 paralyzed
This is the segregation pattern expected for a sin
Lecture 6 6
When we talk about gene position the term locus is used to designate the chromosomal location of a gene. What we are going to do is to map genes relative to one another. To begin, we need two genes on the same chromosome. Last lecture we saw
Lecture 5 5
Until now our analysis of genes has focused on gene function as determined by phenotype differences brought about by different alleles or by a direct test of function the complementation test. For the next six lectures our analysis will be co
Lecture 7 7
Last time we discussed how to measure the distance between two genes on the X chromosome. To do this we used the trick of looking only at male progeny so the genotype of the X chromosome could be scored directly since these flies only carry o
Lecture 9 9
By way of review, lets consider the general question of how genetic mapping studies can be used to locate a gene that has been identified by an allele with an interesting phenotype. For example, the CLOCK mutation in mouse was identified as a
7.03 Lecture 28-30
11/17/03, 11/19/03, 11/21/03
Lecture 28: Polymorphisms in Human DNA Sequences SNPs SSRs
7.03 Lecture 28-30
11/17/03, 11/19/03, 11/21/03
The methods of genetic analysis that you have been learning are applicable to mammals - even to hu
Lectures 29-30: Statistical Evaluation of Genetic Linkage Phase Lod scores
genetic linkage mapping
We genotype the six members of the family for SSRs scattered throughout the genome (which spans 3300 cM)- one SSR must be within 10 cM of the Huntington's g
You are doing a three-point cross in an attempt to map the following genes. The allele of
hh produces bar-shaped eyes, the allele of tx produces the taxi wing position, and the
allele of slo alters response of a y to ethanol.
Table of phenot
Which of the following describes bidirectional DNA replication?
The figure shows a DNA strand which has a free 5' phosphate and a free 3' hydroxy. What you can't see is that it