Question 1: The reaction for the cleavage of fructose 1,6-bisphosphate to
dihydroxyacetone phosphate and glyceraldehyde 3-phosphate is catalyzed by the
enzyme fructose 1,6-bisphosphate aldolase and has a standard free ener
You believe a substrate fits into a cleft like a key into a lock, but your
roommate does not. Who is right?
Two different theories exist about how enzymes bind to substrates. The first
theory is the lock and key model. In this model the su
None as of 8 PM, Thurs., 11 Sept.
Four Levels of Structure in Proteins
Primary Structure of Bovine Pancreatic RNAse A
Amino Acid Sequence Determines Protein Struct
None as of 8 PM, Sun., 14 Sept.
Primary structure dictates secondary and tertiary structure
Newly-made (Nascent) State Folded (Native) State
n-2 n-1 n
of Protein 1
n-2 n-1 n
of Protein 2
HOW does primary structure determine the 3D fold?
Explain how a metabolic pathway can contain an energetically unfavorable
reaction yet still occur.
Multiple ways exist that a metabolic pathway with an energetically unfavorable
reaction can occur. The first way is by coupling the unfavora
DRI: 1945 kcal/day
Your Basal Metabolic Rate is: 1168 calories.
1. The DRI I calculated from the USDA website was 1945 kcal/day. At my
current activity level this is how many calories I need to ingest to maintain
my current body weight. Which means this i
1. Why is it more sensible for phosphofructokinase, rather than hexokinase, to
be an important control step?
Committed steps in a reaction are steps that are the irreversible reactions unique to
the pathway. In glycolysis the first committed
1. Why are membranes impermeable to most substances?
Membranes are impermeable to most substances due to their bilaminer structure.
Most membranes are made up of a lipid bilayer, composed of two layers of lipids,
their hydrophilic head groups
How is water able to be a solvent for so many biological molecules?
Water has unique chemical and physical properties that allow it to be a solvent
for many biological molecules. The fact that water is an electronegative atom
makes gives it
Describe the relationship between fatty acid chain length, saturation, and
the melting point or fluidity of fatty acids.
Fatty acids are the main source of fuel for the body and vary in chain length and
degree of unsaturation. Single bonde
In the Central Dogma, Francis Crick proposes three classifications of general
information transfer of biological information. The first classification is replication
of DNA. In replication, the double helix DNA strand is split and DNA polymerase
Chemiosomotic Hypothesis One:
When protons are pumped across membranes against their concentration gradient
is causes an electrochemical gradient across that membrane. During oxidative
metabolism, this gradient drives ATP synthesis as e
Kuriyan Lecture Outlines
MCB 100A / CHEM 130 Fall 2016
Outline of John Kuriyans lectures.
Note: This outline is a rough guide - the actual pace of the lectures might vary somewhat.
Numbers in parenthesis are the required readings from
The Molecules of Li
Adjustment to Lecture Schedule and Material: We will not formally cover anything more about antibodies (other than the ELISA assays we already discussed) and you will not be responsible for any of the material in Chapter 5 of your textbook o
There is no "Problem Set #5". Review Session for Exam #1: 5-7 PM, Room 10, Evans Hall, Wednesday evening, Oct. 1st EXAM #1:
THURSDAY EVENING, OCTOBER 2 6:00-8:30 PM
A biomembrane demarcates the cell boundary and delimits each organelle co
MCB102 Exam 2 preparation Time: Wednesday, November 5, 2008 6PM for two hours from the actual start time. No calculators. Room/student arrangement 2050 VLSB 429 seats 10 Evans 238 seats 145 Dwinelle 226 seats 160 Kroeber 138 seats Description of exam 1. C