Asthma affects over 22 million Americans with allergic asthma being the most prevalent form of asthma
. It is primarily seen in western civilizations with rural areas having less cases of the disease . The
symptoms of the disease
Adenosine Deaminase Deficiency
Adenosine Deaminase Deficiency or ADA-SCID (severe combined immunodeficiency) is a rare
autosomal recessive disease that causes severe immunodeficiency in patients. It can only be acquired
when both parents possess copies of
1. What is the difference between the red blood cells used in the direct Coombs test and the indirect
The patients red blood cells are used in the direct Coombs test and if positive means that the
anti-human globulin attaches to eithe
CD40 Ligand Deficiency is caused by a gene mutation in the CD40 ligand gene. CD40 ligand is
expressed on T-cell surfaces and is involved in T-cell signaling to B-cells to undergo isotype switching
from IgM to IgA/IgE/IgG1. Isotype switching is mediated wh
M13 Assignment: The Scramble for the Scramblase
What is a mimetic? What makes Eltrombopag a TPO mimetic?
A mimetic is a drug compound that provides the same or similar effects of another
compound of interest. Eltrombopag does this by activation of the Jak-Stat and MAPK pathways
which is the pathway th
Module 3 Assignment 1
Watch this video and answer the following questions.
1. Describe in a couple of sentences what drives oxygen release from hemoglobin.
2. How does the oxygen-hemoglobin dissociation curve demonstrate the phenomenon of
Insulin-Dependent Diabetes Mellitus
Insulin-Dependent Diabetes Mellitus, also known as type-1 diabetes, is a chronic illness that is characterized by the
bodys inability to produce insulin. About 156,000 new cases are reported every year with ~19.7 cases
Module 3 Assignment 1
Looking at figure 1, explain why EPO treatment worked better to restore normal RBC counts than
Explain why not all cases of anemia will benefit from EPO treatment. Enumerate cases that would
EPO treatment worke
M11 Assignment: Drug Safety: Double Jeopardy Submit Assignment
After reading Nature Double Jeopardy article, answer the following questions. If you include additional information-other than from the course or our
textbook-cite your source/s.
M10 Assignment: Stem Cells: Bad Seeds
After reading Nature Bad Cells article, answer the following questions. If you include additional information-other than from the
course or our textbook-cite your source/s.
On the seventh paragraph on page S1
M9 Assignment: Combined Forces
1. Discuss how combination multi-drug therapy can be more effective in causing more durable
remission than sequential single-drug therapy. (3 pts)
Combination multi-drug therapy can be more effective because it can target mu
Tumor Suppressor and Oncogenes
Proto-oncogenes and tumor suppressor genes determine whether the cell will divide.
Proto-oncogenes are genes that normally cause cells to divide and when they mutate (become
oncogenes) cause excessive cell division.
M12 Assignment: Novel Oral Anticoagulants
List the anticoagulants mentioned in the article, what they are, as well as their pros and cons. (4 pts)
What are some of the differences between clinical trials and real-world patient settings? (2 pts
M8 Assignment: WBCs, Fat, and Diabetes
"White Blood cells, Fat, and diabetes: how neutrophils mediate insulin resistance"
The article mentions evidence or results that support the hypothesis that neutrophils mediate insulin resistance. Give
at least tw