Genome Refers to the total genetic composition of an organism or species.
Genomics Refers to the molecular analysis of the entire genome of a species.
Functional Genomics Examination at the level of many genes, how the components of a genome
interact to p
Functional Genomics Review
Functional Genomics The goal is to understand the roles of genetic sequences DNA, RNA, and amino
acid sequences in any given species.
- Human genome has ~22,000 different genes, yet a muscle cell expresses only a subset of
Biological Evolution is a heritable change in one or more characteristics of a population or species
from one generation to the next
- Theory of Evolution was proposed by Charles Darwin
o HMS Beagle voyage (1832-1836)
o Book: On the Origin of Species by M
Mutation Heritable change in genetic material
Mutagens Agents known to alter DNA structure
o Nitrous Acid
o Nitrogen Mustard
o Ethyl Methanesulfonate
o Proflavin (Type of Acridine
Lactose/ No Glucose (High cAMP)
No Lactose/ No Glucose (High cAMP)
Lactose/ Glucose (Low cAMP)
No Lactose/ Glucose (Low cAMP)
CAP Site (Catabolite Activator Protein
Developmental Genetics concerned with the roles genes play in orchestrating the changes that occur
Pattern refers to the spatial arrangement of different regions of the body.
- At the cellular level, the body pattern is due to arrangem
- Process by which DNA segments that are similar or identical to each other break and rejoin to
form a new combination
- Between homologous chromosomes
- Found in all species
- Enhances genetic diversity
- Helps repair DNA
Regulation of trp
- Encodes enzymes involved with the systhesis of the amino acid tryptophan
- Is a corepressor.
- Binds to repressor creating a conformational change of the protein allowing it to bind to the trp
operator and inhib
Minh Hoang (Jim)
The Titin Game
The combination CAP appears 1 time in the sequence.
The combination PAK appears 25 times in the sequence.
The combination KAP appears 15 times in the sequence.
The combination TIA appears 3 times in the sequence.
Lab 4: Cells and Microscopy
Introduction: In todays lab, we will examine the smallest unit of lifecells. Because most cells are
so small, they require the use of microscopes to see them. There are two types of cells in
Lab 3 Biological Macromolecules Part 2 Unknown Identification
(some material adapted from C.W. Pratt, Journal of Microbiology & Biology Education, May 2011, p44-45)
to identify and c
February 4, 2015
Lab 2: Biological Macromolecules Part 1
Introduction: Almost all of the food we eat comes from plants and animals. Plants and animals contain
mainly water and carbon based organic compounds, which are m
Name: LaNyce Johnson
NSC 1406 Fall 2014
Lab 1 Hypothesis-based science
Objective: To formulate hypotheses and test them using basic laboratory
Introduction: The scientific method relies on the ability to formulate a testable,
NSC 1406 Spring 2015
Lab 7 - Harvest of Fear
Due: at the end of the movie today
1. In your own words, explain what Bt is. (2 pts)
2. In your own words, explain how Bt corn was made. (2 pts)
3. Answer the following questions pertai
Lab 8: Bacterial transformation (part 1)
Previously, we discussed the process of transcription, translation and mutation as it relates to a
cells ability to make proteins. As discussed, this is
Calculation of transformation efficiency
Due at the end of lab for 10 points
The score from this sheet will be combined with the transformation questions you turned in last week for
a total of 20 points.
When using transformation techniques
Lab 9: Chemical control of microorganisms
Adapted from Suzanne Anglehart, Annie Voyles, and Bonnie Jo Bratina
BACKGROUND: Wash your hands! This is something we all learn at a very early age in order
to maintain good hygiene. It is hard to b
NSC 1406 Spring 2015
Lab 6 Transcription and translation
Objective: To become familiar with the processes of transcription and translation.
Introduction: In this lab, we will use a manipulative kit to discover the amino acid
sequences encoded by se