Cellular Neuroscience Exam 2 Fall 2015
1) The flow of ions through individual K+ channels (delayed-rectifier type) is voltagedependent, because
a) depolarization (between ~-40mV and 0mV) increases the probability of the channel to
b) these channels h
Cellular Neuroscience Test 2 (Midterm)
1. The basis of neuronal excitability is the rapid displacement of _ through
the lipid bilayer: electrically charged ions
2. The most abundant cations in a physiologic solution usually are: Na ions
3. Ion channels ar
1) Which of these are general features of metabotrpic receptors:
a) Proteins consist of 7 transmembrane domains.
b) G proteins bind to both the loop between domains V and VI and the C terminus
c) none of the above
d) All of the above.
2) The nicot
1. Adding KCL to external medium what would happen to RMP?
a. Membrane would be depolarized (making outside more like inside)
2. MS is?
a. Myelin is damaged
3. MP=-76mV and equilibrium potential is -55mV. How could make K+ move into the
1. Which of the following is NOT true about Na channels.
a) They have voltage sensors
b) They do not have any mechanism for inactivation
c) At potential more positive than ENa current seen is outward
d) Shows ion selectivity
2. Active transporters
K now the differene between metabotropic and ionotropic Know that epinephrine have second messenger The G-protein have low affinity for alpha, beta, gamma. When there is no receptor bound t hen there is no affinity. Receptor has high affinity for GDP-boun
Cellular Neuroscience Test 2 (Midterm) 1. The basis of neuronal excitability is the rapid displacement of _ through the lipid bilayer: electrically charged ions 2. The most abundant cations in a physiologic solution usually are: Na ions 3. Ion channe
Mechanisms of Long-term changes in
LTP(D) Pre- or post- synaptic ?
Although long-term plasticities at some synapses
seem to have a presynaptic origin, two types of data
indicate a strong post-synaptic component in many
Reversible addition of saturated 16-carbon palmitic acid to
specific cysteine residues through the formation of a labile
thioester bond (thiopalmitoylation or S-palmitoylation).
Although a few proteins are irreversibly palmitoylate
NSC 4352 Practice Exam
Neurotransmitters and Their Receptors
1. Which of the following are the physically largest neurotransmitters?
2. Acetylcholine is used as a neurotransmitter at
The neuromuscular junction