Did Mendel Fake his Data?
Gregor Mendel
Ronald A Fisher
Case Study: The Binomial Distribution
Fall 2016
Biostat 310
227
The Controversy
In 1866 Gregor Mendel wrote a paper reporting results from
experiments crossing various strains of peas
This work, al
Final Review
BIOSTAT 310
1
Summary of Activity
Calcium (Ca) deficiency is associated with higher risk of
hypertension, and hypertension is associated with an increased risk of
cardiovascular disease. We therefore expect Ca deficiency to be
associated with
Food Safety
SPH380 History and Practice of Public Health
Fall Quarter 2016
Instructors:
Tao Sheng Kwan-Gett, MD MPH
Suzinne Pak-Gorstein, MD MPH PhD
Teaching Assistants:
Natasha Ludwig-Barron
Bridget Whitney
SCHOOL OF PUBLIC HEALTH
Announcements
Thank yo
Name _Student ID _ Score _
Last
First
I) Multiple choice (12 questions, 5 points each)
1. An ideal parallel plate capacitor with a plate separation of d = 5.00 10-3 m and a capacitance of
C = 4.00 10-6 F is charged so that the total charge on the upper pl
Biostat 310
Homework 2
Submit your responses only (not the questions) to the CANVAS course website
DUE: 10/14/16, 11:30am
TOTAL: 10 POINTS
There are a total of 8 graded points (questions indicated by *) and then an additional 2 points in total
for the add
Biostat 310
Homework 3
Submit your responses only (not the questions) to the CANVAS course website
DUE: 10/21/16, 11:30am
TOTAL: 10 POINTS
There are a total of 8 graded points (questions indicated by *) and then an additional 2 points in total
for the add
Biostat 310
Homework 1
Submit your responses only (not the questions) to the CANVAS course website
DUE: 10/7/16, 11:30am
TOTAL: 10 POINTS
There are a total of 8 graded points (questions indicated by *) and then an additional 2 points in total for the
addi
Body Fat Measurement
Winter 2016
Biostat 310
1
Correlation
80
100
120
Hip circumference (cm)
140
160
A scatterplot can be used to display the relationship between
two quantitative measures
The correlation coefficient is used to measure the strength of
a
Review: Hypothesis Testing Steps
1.
Specify the significance level of the test,
2.
State the scientific question
3.
Convert the scientific question into statistical hypotheses (null and
alternative) appropriate for the study design
4.
Choose a reasonable
Prevention of Mother to Child
Transmission of HIV
Winter 2016
Biostat 310
1
HIV and PMTCT
An (untreated) HIV-infected pregnant woman has a
20-40% chance of infecting her infant in utero or
during birth
This gave rise to a generation of HIV-infected babi
HIV and Circumcision
Winter 2016
Biostat 310
0
Winter 2016
Biostat 310
1
Winter 2016
Biostat 310
2
Case Reports
Describe characteristics of a few individual patients
Often, the first description of the disease or phenomenon
Weak study design
No contro
Rachel Lee
Student ID: 1331935
BIOST 310 AA
Homework 2
1. a) Prevalence of HIV+ = 61/475 = 0.1284 or 12.84%
Prevalence of IVDU = 136/475 = 0.2863 or 28.63%
b) Prevalence of HIV+ without IVDU = 27/88 = 0.3068 or 30.68%
Prevalence of HIV+ with IVDU = 61/88
Biostatistics for the
Health Sciences
(Biostatistics 310)
Instructor: Lyndia Brumback
Cartoons and images in these notes are from
Gonick L. Cartoon Guide to Statistics. HarperPerennial, New York, 1993.
Fisher L and vanBelle G. Biostatistics: A Methodology
Rachel Lee
ID #: 1331935
BIOST 310 AA
Homework #4
1.
a) 40/318 = 0.13
b) Left: 10/48 = 0.21, Right: 30/270 = 0.11
These two probabilities are different.
c) 278/318 = 0.87
d) 30/220 = 0.14
e) 18/48 = 0.375
2.
a) sensitivity = 180/200 = 0.9
b) specificity =
Did Mendel Fake his Data?
Ronald A Fisher
Gregor Mendel
Winter 2016
Biostat 310
1
The Controversy
In 1866 Gregor Mendel wrote a paper reporting results
from experiments crossing various strains of peas
This work, although not appreciated at the time, is
Rachel Lee
Student ID: 1331935
BIOST 310 AA
Homework 1
1) Fiebig stage would be considered an ordinal categorical variable because under
the category of the Fiebig stage, the numbers I VI have a meaningful order that
signify the progression of HIV.
2) Med
Rachel Lee (131935)
BIOST 310 AA
Homework 6
1) a.
(i) statistic
(ii) 0.1 2 * (0.1*0.9)/1687) = (0.0146, 0.0853)
b.
(i) Relative Risk
(ii) Chi-square test
(iii) H0: Medication does not have an adverse response
HA: Medication does has an adverse response
2)
Rachel Lee
Student ID: 1331935
January 26, 2016
Homework #3
1. * Answer: b) A cohort study
2. * Answer: b) The comparison of outcome between treatment and control groups
is likely confounded by other differences between the groups
3. * (i) experimental &
Rachel Lee
BIOST 310 AA
Homework 7
1. Reject the null because p<0.05
2.
a) two sample unpaired t-test
b) 0.32
c) Do not reject H0 and conclude there is no strong evidence that particulate
levels are different in urban vs rural areas
3. b. Use a very small
Review for BIOST 310 Final
1
Topics covered since Midterm II
CLT; Sampling Distribution and Confidence
Interval for
Hypothesis testing (H0 and HA, , Type I and
Type II error, P-value, power, sample size)
One sample test for proportion (binomial or Z
t
Practice Problems:
1. A study enrolled 240 non-smokers with lung cancer and 260 non-smoking controls. The
investigators then determined whether each participant had been exposed to the cigarette
smoke of a spouse for at least 6 months ("exposed to passive
Biostat 310
Homework 5
Submit to the CANVAS course website
DUE:11/06/15, 11:30am
[14 points]
There are a total of 12 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, graded
Cin Yu Hsieh
Biostatistics 310
Term Paper
Your Hardcore Run May Be as Dangerous as Sitting Around Doing Nothing, is a news report
aiming to summarize the potential findings of a longitudinal cohort study on the association
between different level of joggi
Biostat 310
Homework 8
Submit to the CANVAS course website
DUE: 12/11/15, 11:30am
[14 points]
There are a total of 12 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, grade
Biostat 310
Homework 7
Submit to the CANVAS course website
DUE:12/04/15, 11:30am
[15 points]
There are a total of 13 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, graded
Biostat 310
Homework 6
Submit to the CANVAS course website
DUE:11/13/15, 11:30am
[15 points]
There are a total of 13 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, graded
Biostat 310
Homework 4
Submit to the CANVAS course website
DUE: 10/30/15, 11:30am
[14 points]
There are a total of 12 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, grade
Biostat 310
Homework 3
Submit to the CANVAS course website
DUE: 10/23/15, 11:30am
[15 points]
There are a total of 13 graded points (questions indicated by *) and then an additional 2 points in total for the
additional questions without an asterisk, grade