Week 9: Cardiovascular System
1. Discuss the mechanism of action of selected diuretics.
2. Discuss the action, indications, dosage for clients receiving cardiac glycosides.
3. Describe the mechanism of action, use and adverse effects of angiotensi
Gold Standard Drugs & Study Guide for Exam I: NRS- 312- F 2011
I have identified the drugs to consider as gold standard drugs for purposes of
studying for the exam. I do want to discourage you from spending too much time
on memorizing names. Instead, your
Aspart (Novolog): give insulin when tray arrives on the flood, 15 min before breakfast.
Lisinipril (Prinvil) ACE inhibitor to treat hypertension: electrolyte imbalance most likely
to occur is hyperkalemia
CHF; treated with Lasix, symptom that
Regulation of cardiovascular system
Maintain blood flow to the brain
Redistribution of blood
Compensation for loss of blood
Regulation of body temperature
Regulate blood flow to the skin
Promote secretion of sweat
1. List the four basic processes of pharmacokinetics; duration of action, metabolism,
elimination, onset of action. (peak effect, and half-life.)
a. Pharmacokinetics: impact of the body on the drugs, the movement of the
drug through the body. The phases t
o Dilate vessels (arterioles) causing a decrease in cardiac afterload (force the
heart works against to pump blood).
Decreasing afterload resulting in cardiac output and tissue
perfusion to increase.
o Drugs that dilate veins reduce the forc
Vasodilation decreases resistance to flow
Vasoconstriction increases resistance to flow
Heart rate is increased by sympathetic and decreased by parasympathetic
Preload: amount of tension or stretch applied to a muscle prior to
Week 1 and 2: Introduction Overview of Drug Development and Regulation
1. List the three major properties of an ideal drug.
b. Ease of administration
2. Discuss the nurses responsibility regarding the administration of prescribe
Propranolol- a sympatholytic non-selective beta-blocker. Sympatholytics are used
to treat hypertension, anxiety and panic
Diabetes mellitus or hyperthyroidism, since signs and symptoms of
hypoglycaemia may be masked. Peripheral vascular disease and Raynau
Lidocaine numbs area- local adverse effects- Central nervous system,
cardiovascular system, Allergic reactions,
Succinylcholine- Succinylcholine has the briefest duration of action of all
neuromuscular blocking drugs, making it a drug of choic
Central Nervous System
1. Discuss the significance of the blood-brain barrier.
Anatomy of capillaries in the CAN, there are tight junctions between the cells that
compose the walls of most capillaries in the CAN. So tight they prevent drug
passage. A dru