Module 17 Cancer Chemotherapy
Cancer refers to the uncontrolled proliferation of cells. Cancer cells are often
referred to as neoplastic, meaning they have abnormal and uncontrollable cell
3.1 BODY COMPARTMENTS
q Drugs distribute into compartments in the body where they may be stored, metabolized,
excreted or exert their pharmacological effect.
q The bodys compartments include:
PHARMACODYNAMICS DOSE RESPONSE RELATIONSHIPS
Pharmacodynamics is the study of what the drug does to the body.
In pharmacodynamics we study the biochemical and physiological effects of drugs and the
Module 14 CNS Drugs Part II
Epilepsy is a neurological disorder that
produces brief disturbances in the normal
electrical activity in the brain.
Epilepsy is characterized by sudden, brief
DRUGS TO LOWER BLOOD
CHOLESTEROL AND TRIGLYCERIDES
CORONARY HEART DISEASE
Coronary heart disease occurs when coronary blood circulation fails to adequately supply the
heart with blood.
Drugs can interact with each other
or components in our diet to
produce complicated responses.
Drug-drug interactions may occur
whenever a patient takes two or
Module 13 Drugs for Hypertension
Hypertension is simply defined as elevated systemic arterial blood pressure.
Blood pressure is a measurement of the force against the walls of your
Module 14 CNS Drugs Part I
14.1 Introduction to Neuropharmacology
Neuropharmacology is the study of how
drugs affect the function of the central
There are many disorders of the central
ADVERSE DRUG REACTIONS AND
10.1 Adverse Drug Reactions
Adverse drug reactions (ADRs) are the unintended and undesired responses from drugs.
Adverse drug reactions are an enormous societal health probl
4.1 DRUG METABOLISM
Metabolism is the enzyme mediated
alteration of a drugs structure.
Metabolism is also referred to as
Sites of drug metabolism include:
Duse Respunse Relationships
/—= 1. Te identify):r the three phases of the dese-
2. Te select the drug with the highest efficacy en a
s Ts select the drug with the highest
/—= 1. Tc be able tc determine the EDEU en a frequencyr
2. To be able tc calculate the therapeutic index of
drugs and aecertain whether a drug is eafe.
a Tc deﬁne the speciﬁc
Adverse Drug Reactions and
Medication Errors CTIVES
1. To be able to identify the type of adverse drug
reaction a patient is experiencing from a list of their
symptoms and a description of their exposure.
2. To describe the di
Vd= D/C D= total amount in the body, C= plasma concentration of drug
Dose rate= plasma concentration x clearance
T1/2= 0.693 x Vd
Loading dose= target drug plasma concentration x Vd
Therapeutic Index (TI)= TD50/ED50 (or LD50/ED50)
The skin protects us from the external environment. Its a barrier for our insides.
It does this by using a physical barrier, but it also has some cells from the immune
It helps us to keep water inside of our body.
The outermost lay